Radiation-associated angiosarcoma after autologous breast reconstruction: report of two cases in a plastic surgery unit

AbstractRadiation-associated breast angiosarcoma is a rare diagnosis but is commonly reported. Angiosarcoma occurring in non-breast tissue in breasts that have been reconstructed with autologous tissue following mastectomy is extremely rare. In our unit, we have managed two patients with angiosarcoma arising in non-breast tissue autologous reconstructions. Our report emphasises that any tissue treated with radiotherapy —that is, the residual mastectomy skin flaps or non-breast tissue autologous reconstructions—are at a risk of secondary angiosarcoma. We also discuss recommended surgical management, surveillance and genetic testing.Level of Evidence is V, risk study.
Source: European Journal of Plastic Surgery - Category: Cosmetic Surgery Source Type: research