Vitamin D Levels in Patients with Recurrent Herpes Labialis

Viral Immunology, Ahead of Print.
Source: Viral Immunology - Category: Allergy & Immunology Authors: Source Type: research

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(Harvard Medical School) Scientists have used the gene-editing tool CRISPR-Cas9 to disrupt both latent reservoirs of the herpes simplex virus and actively replicating virus in human fibroblast cells. Experiments pinpoint weak spot that can make the virus susceptible to gene editing.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
In 2018, the number of bacterial sexually transmitted infections (STIs) reported in the United States reached an all-time high. This is worrisome for many reasons. Having an STI can raise risks for HIV, infertility, pregnancy complications, and infant death. Fortunately, all of these outcomes can be avoided if people receive appropriate treatment. What are STIs? STIs are illnesses caused by microorganisms passed between people during sex. An STI can affect anyone who is exposed to it. Syphilis, gonorrhea, and chlamydia are the most common bacterial infections. Trichomoniasis, a protozoan infection, is also diagnosed freque...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Adolescent health HIV Men's Health Relationships Sexual Conditions Women's Health Source Type: blogs
CONCLUSIONS: A complete recovery of cranial nerves VII and VIII in the course of RHS can be achieved. PMID: 31816219 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
Viperin is an interferon-inducible protein that responsible for a variety of antiviral responses to different viruses. Our previous study has shown that the ribonuclease UL41 of herpes simplex virus 1 (HSV-1) can degrade the mRNA of viperin to promote HSV-1 replication. However, it is not clear whether other HSV-1 encoded proteins can regulate the function of viperin. Here, one novel viperin associated protein, glycoprotein D (gD), was identified. To verify the interaction between gD and viperin, gD and viperin expression plasmids were firstly co-transfected into COS-7 cells, and fluorescence microscope showed they co-loca...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
TORCH infections caused by Toxoplasma gondii (TOX), rubella virus (RV), cytomegalovirus (CMV) and herpes simplex virus 1,2 (HSV-1,2) are associated with congenital anomalies. The study aimed to analyze the charac...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research
Abstract BACKGROUND: Rapid identification of human herpesviruses from lesion swabs is necessary for timely initiation of antiviral treatment, especially with infections involving neonates and immunocompromised individuals. The aim of the study was to investigate the results of an in-house polymerase chain reaction (PCR) test for herpesviruses in patients with symptoms suggestive for a herpesvirus infection. PATIENTS AND METHODS: In this single center retrospective study the results of 3677 lesion swab specimens tested for human herpes simplex virus 1 and 2 (HSV 1 and 2) and varicella zoster vir...
Source: Wiener Klinische Wochenschrift - Category: General Medicine Authors: Tags: Wien Klin Wochenschr Source Type: research
HSV-1 is a common pathogen that infects 50 –90% of the human population worldwide. HSV-1 causes numerous infection-related diseases, some of which are severely life-threatening. There are antiviral medications ...
Source: BMC Microbiology - Category: Microbiology Authors: Tags: Research article Source Type: research
This infant was born at 34 weeks 5 days estimated gestational age secondary to premature rupture of membranes. Prenatal history was unremarkable with negative infectious serologies, including herpes simplex virus (HSV), and normal anatomy scan at 20 weeks ’ gestation. In the delivery room, vesicular lesions were noted that quickly denuded leaving behind erythematous plaques (Figure 1A). In the delivery room, the infant displayed myoclonic movements. When an EEG was recorded, the aforementioned movements had no electrographic correlate.
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Visual Diagnosis Source Type: research
Henke A Abstract Infections with the herpes simplex virus type 1 (HSV-1) are common and widespread. Most infections remain undetected but severe forms may develop in newborns and in immunocompromised patients. Moreover, HSV-1 might be involved in the pathogenesis of atherosclerosis, which may include viral infection of the endothelium. Antiviral therapy is efficient to treat symptomatic patients. However, an increasing accumulation of resistance-associated mutations has been observed in the viral genome. Thus, new antiviral strategies are focused on host factors. Among others, signaling of bioactive sphingolipids ...
Source: Virus Research - Category: Virology Authors: Tags: Virus Res Source Type: research
Purpose: To report the clinical outcome and postoperative course of Descemet membrane endothelial keratoplasty (DMEK) in irreversible corneal edema due to herpes simplex virus (HSV) endotheliitis. Methods: This is a retrospective, noncomparative, interventional case series. Nineteen eyes of 19 patients underwent standard DMEK combined with cataract surgery (triple DMEK) between May 2016 and April 2018. All patients received perioperative oral acyclovir (ACV) and prednisolone. Patients were followed up on day 1, on day 7, at 1 month, and then at 3 monthly intervals. Preoperative and postoperative best spectacle-correct...
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
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