New imaging tool for diagnosing heart disease

(Lawson Health Research Institute) An international team led by scientists from Lawson Health Research Institute and Cedars-Sinai Medical Center are the first to show that Magnetic Resonance Imaging (MRI) can be used to measure how the heart uses oxygen for both healthy patients and those with heart disease.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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AbstractPurpose of ReviewThe purpose of this paper is to review current and new modalities to image key biological processes in ischemic heart disease and after myocardial infarction non-invasively.Recent FindingsNew imaging targets have been developed to detect and quantify myocardial damage after ischemia. Although positron emission tomography (PET) has been leading the development of new probes in the past, continuous improvements of magnetic resonance imaging (MRI) together with the development of new novel MRI contrast agents opens new research avenues including the combination of both PET and MRI to obtain anatomic, ...
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research
AbstractPurpose of ReviewTo discuss the role of cardiovascular computed tomography (CT) in diagnosing and managing a spectrum of cyanotic congenital heart defects before and after repair and to review practical imaging considerations in patients with specific cyanotic lesions.Recent FindingsAs CT technology has rapidly advanced and radiation doses have dramatically decreased, cardiovascular CT has provided a lower-risk, high-quality alternative to diagnostic cardiac catheterization or cardiac magnetic resonance imaging (MRI) and has been increasingly utilized in nearly every type of cyanotic congenital heart defect.Summary...
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research
AbstractCongenital pulmonary artery (PA) anomalies comprise a rare and heterogeneous spectrum of disease, ranging from abnormal origins to complete atresia. They may present in early infancy or more insidiously in adulthood, often in association with congenital heart disease such as tetralogy of Fallot or other syndromes. In recent years, cross-sectional imaging, including computed tomography (CT) and magnetic resonance imaging (MRI), has become widely utilized for the noninvasive assessment of congenital PA diseases, supplementing echocardiography and at times supplanting invasive angiography. In this article, modern CT a...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
Myocardial oxygenation—the ability of blood vessels to supply the heart muscle (myocardium) with oxygen—is a critical determinant of cardiac function. Impairment of myocardial oxygenation is a defining feature of ischemic heart disease (IHD), which is caused by pathological conditions that affect the blood vessels supplying oxygen to the heart muscle. Detecting altered myocardial oxygenation can help guide interventions and prevent acute life-threatening events such as heart attacks (myocardial infarction); however, current diagnosis of IHD relies on surrogate metrics and exogenous contrast agents for which man...
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Research Articles Source Type: research
ConclusionRight SCA with congenital absence of the LCA is one of the rarest coronary artery anomalies. In a significant percentage of patients it is associated with ischemia and can be life-threatening. CCTA and MRI are the modalities of choice for diagnosis and risk stratification.ResumoIntroduçãoArtéria coronária única (ACU) sem cardiopatia congénita associada é uma entidade rara. Maioria dos casos é assintomática e achados acidentais, mas podem causar isquémia, insuficiência cardíaca congestiva e morte súbita (MS).Caso clíni...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
AbstractPurpose of ReviewThe purpose of this review is to answer the question whether left ventricular hypertrophy (LVH) could be considered a therapeutic target in patients with hypertension. To fulfill this purpose, we briefly outline different methods of measuring LVH, then discuss the current evidence and unresolved controversies regarding the relationships among LVH, blood pressure (BP), and cardiovascular disease (CVD) outcomes.Recent FindingsThe methods and criteria used for defining LVH in clinical studies lack consistency and are inherently different. Electrocardiogram (ECG) has been the most common method, but so...
Source: Current Hypertension Reports - Category: Primary Care Source Type: research
CONCLUSIONS: The adaptive k-nearest neighbors algorithm allowed an individual-centric assessment of each individual's metabolic phenotype moving beyond discrete categorizations of body composition. Within obesity and NAFLD, this may help in identifying which comorbidities a patient may develop and consequently enable optimization of treatment. PMID: 31094076 [PubMed - as supplied by publisher]
Source: Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Obesity (Silver Spring) Source Type: research
ConclusionSSH is a rare situation of acenocoumarol bleeding incident, it should be evoked in any patient treated by this molecule with signs of spinal cord compression.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conditions:   Congenital Heart Disease;   Pulmonary Arterial Hypertension Interventions:   Other: 4D Flow magnetic resonance imagery;   Procedure: Cardiac catheterization Sponsor:   Centre Chirurgical Marie Lannelongue Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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