Factors Associated with the Development of Secondary Multidrug ‑resistant Tuberculosis

Conclusions:Government of India should devise strategy to prevent interruption of treatment to stop the emergence and spread of MDR ‑TB. We need to better integrate TB control activities with diabetes and tobacco control programs for better health outcome among patients.Keywords:India, multidrug resistance, risk factors, tuberculosis
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research

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Publication date: Available online 17 July 2019Source: Global HeartAuthor(s): Jessica Ying-Yi Xie, Matthew R. Solomons, Mahmood Ahmad
Source: Global Heart - Category: Cardiology Source Type: research
CONCLUSIONS Apigenin protects renal tubular epithelial cells against high glucose-induced injury through suppression of oxidative stress and inflammation via activation of the Nrf2 pathway. PMID: 31309931 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Authors: Liu J, Bhuvanagiri S, Qu X Abstract The aim of the present study was to investigate the effect of Lycopus lucidus Turcz (LT) on diabetic retinopathy (DR) and its underlying mechanisms. SD rats and human retinal microvascular endothelial cells (HRECs) were applied for establishment DR model. HE and TUNEL staining were used to evaluate the pathological changes and apoptosis of retinal ganglion cells. Additionally, retinal vessels were detected by immunofluorescence staining with CD31 and VEGF. The function of BRB was observed using Evans blue. Moreover, the oxidative stress, inflammation and angiogenesis ass...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Publication date: Available online 17 July 2019Source: Neuroscience LettersAuthor(s): Anamaria Falcão Pereira, Lus Mário Silva Pereira, Cristiane Maria Pereira Silva, Bruno Wesley Freitas Alves, Jéssica Sales Barbosa, Francisco Maxwell Martins Pinto, Ana Carolina Pereira, Karla Oliveira Silva, Renata Bessa Pontes, Nylane Maria Nunes Alencar, Roberto César Pereira Lima-Júnior, Mariana Lima ValeAbstractOxaliplatin is a third-generation platinum drug commonly used as the first line treatment of metastatic colorectal cancer. Oxaliplatin-based anticancer regimens course with dose-limiting neur...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 17 July 2019Source: Neuroscience LettersAuthor(s): Alagudurai Krishnamoorthy, Murugan Sevanan, Sugumar Mani, Mangayarkarasi Balu, Sravani Balaji, Ramajayan PAbstractParkinson disease occurs due to the depletion of dopaminergic neurons in brain resulting in decreased dopamine level and abnormal protein aggregation. Chrysin is a flavonoid which possesses pharmacological properties against various diseases like hypertension, diabetes, cancer, etc. According to the recent literatures, it is evidenced that chrysin protects mice against Focal Cerebral Ischemia/Reperfusion Injury. The present st...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
We present a case of a five-year-old child with clinical features mimicking several diseases, including tuberculosis. After failure of treatment based on the suspected diagnosis, an axillary lymph node biopsy showed noncaseating granulomas compatible with sarcoidosis and appropriate treatment was then started.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Publication date: Available online 17 July 2019Source: Trends in Food Science &TechnologyAuthor(s): Lijun Sun, Fredrick J. Warren, Michael J. GidleyAbstractBackgroundα-Amylase plays an important role in starch digestion, the main source of exogenous glucose in the human diet. Retarding glucose absorption through delaying digestion of starchy foods by inhibiting α-amylase in the digestive tract has potential as a management and/or therapeutic approach to type II diabetes. Polyphenols have been reported to have inhibitory activity against the enzyme.Scope and approachThis review provides an overview of struct...
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 18 July 2019Source: The Crop JournalAuthor(s): Awnindra Kumar Singh, A. Velmurugan, Debjyoti Sen Gupta, Jitendra Kumar, Ravi Kesari, Aravind Konda, Narendra Pratap Singh, Sibnarayan Dam Roy, Utpal Biswas, R. Rahul Kumar, Sanjay SinghAbstractBeach pea or beach cowpea (Vigna marina (Burm.) Merr.) belongs to the family Fabaceae. It is a close relative of cultivated Vigna species such as adzuki bean (V. angularis), cowpea (V. unguiculata), mung bean (V. radiata), and blackgram (V. mungo), and is distributed throughout the tropics. With its ability to tolerate salt stress, beach pea has great ...
Source: The Crop Journal - Category: Food Science Source Type: research
AbstractOur study aims to define the epidemiology of carbapenem resistance mechanisms in clinical isolates ofPseudomonas aeruginosa (PA). We evaluated 11,457 clinical PA strains isolated between 2009 and 2015 at the tertiary care University Hospital in Heidelberg, Germany. Thirty-four percent of the isolates (3867/11,457) were MDR (multidrug-resistant), 16% (1816/11,457) were XDR (extensively drug resistant), and less than 1% (82/11,457) had a PDR (pandrug-resistant) profile. Of those, 23% carried a carbapenemase gene (CPM positive) with 12% VIM-2, 10% VIM-1, and less than 1% IMP-1. Comparing MIC (minimal inhibitory concen...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Authors: Rumende CM Abstract In 2015, 10.4 million people developed tuberculosis (TB) and 580,000 amongst them suffered from multidrug-resistant TB (MDR-TB). From those 580,000 cases of MDR-TB, only 125,000 were detected and reported. A total of 111,000 people began to receive MDR-TB treatment in 2014 while 190,000 MDR-TB patients were estimated to have died, largely due to lack of access to effective treatment. The mechanism of drug resistance can be caused by genetic factors, factors related to previous treatment and other factors such as comorbidity with diabetes mellitus. Although there is some evidence which p...
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research
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