Associations Between Age at Arterial Switch Operation, Brain Growth and Development in Infants with Transposition of the Great Arteries.

CONCLUSIONS: Surgery beyond two weeks of age is associated with impaired brain growth and slower language development in infants with TGA cared for at our center. While the mechanisms underlying this association are still unclear, extended periods of cyanosis and pulmonary over-circulation may adversely impact brain growth and subsequent neurodevelopment.
PMID: 31132861 [PubMed - as supplied by publisher]

Source: Circulation - May 27, 2019 Category: Cardiology Authors: Lim JM, Porayette P, Marini D, Chau V, Au-Young SH, Saini A, Ly LG, Blaser S, Shroff M, Branson HM, Sananes R, Hickey EJ, Gaynor JW, Van Arsdell G, Miller SP, Seed M Tags: Circulation Source Type: research