Chronic widespread pain patients show disrupted cortical connectivity in default mode and salience networks, modulated by pain sensitivity

Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research

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Publication date: Available online 20 August 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Megan N. Wasson
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Conclusion: In this study, the coastal areas of South Korea carry a higher burden than the national population. Additionally, chronic diseases compose the majority of the health burden in coastal areas. Despite the limitation of data, YLD was the best tool available for evaluating the health outcomes in specific areas, and has the advantage of simplicity and timely analysis.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Endometriosis is an estrogen-dependent disease with symptoms of dysmenorrhea, chronic pain, and infertility that affects 6% to 10% of women of reproductive age. Medical or surgical therapy, such as administration of an anti-gonadotropin or ovarian cystectomy, provide effective pain relief. However, neither therapy can be used for patients wishing to become pregnant. Despite the high morbidity, the pathogenesis of endometriosis has not been well elucidated. Several inflammatory cytokines are reported to participate in the onset of endometriosis. Here, we examined the role of interleukin (IL)-1/IL-33 signaling in the develop...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ConclusionDespite the limitations of a retrospective study, we feel our study adds to the growing evidence base that pulsed radiofrequency treatment adjacent to the cervical dorsal root ganglion has a role in the treatment of chronic cervical radicular pain.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
Childhood sexual abuse (CSA) is a physical assault upon the body and considered to be a complex traumatic experience affecting both body and mind. Growing evidence indicates that long-term effects of CSA include maladies such as chronic pain and fibromyalg...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
CONCLUSIONS: We were able to define predictors of admission for patients having LH/RAH managed with an ERAS pathway. Increased ASA physical status, being African American, and increased length of procedure were significantly associated with admission after LH/RAH performed under an ERAS pathway. In addition, the incidences of urgent clinic and ER visits, readmissions, and reoperations within 90 days of surgery were similar for patients who were discharged on the day of surgery compared to those admitted. PMID: 31425219 [PubMed - in process]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
Abstract BACKGROUND: As opioid abuse and addiction have developed into a major national health crisis, prescription of opioids for pain management has become more controversial. However, opioids do help some patients by providing pain relief and improving the quality of life. To better understand the addictive properties of opioids under chronic pain conditions, we used a conditioned place preference (CPP) paradigm to examine the rewarding properties of morphine in rats with persistent nociception. METHODS: Spared nerve injury (SNI) model was used to induce persistent nociception in rats. Nociceptive behavior...
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
ConclusionsA simple noninvasive protocol for managing cTMD with self-help, exercises, and oral devices resulted in clinically and statistically meaningful improvements in pain, function, and quality of life.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
Patients with hidradenitis suppurativa (HS) experience chronic inflammation of the skin with disease exacerbations associated with increased pain, which may necessitate acute treatment. During such exacerbations, patients with HS often present to the emergency department (ED). However, it is unknown if the disease is correctly identified and coded by health care professionals in the ED. A retrospective, single center institutional board review approved chart review of patients who had at least one diagnosis code for “hidradenitis suppurativa” at any time and who received treatment with analgesics for HS-related...
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Introduction: Hidradenitis suppurativa (HS) has been shown to have a negative impact on quality of life, even more so than psoriasis, acne and eczema. Research has only recently focused on the impact HS has on sexual health. HS patients may experience sexual decline due to pain, physical appearance, and diminished sexual desire. Dermatologists who treat this chronic condition are in a unique position to screen these patients for sexual health concerns and provide counseling or specialized referral
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
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