Development of practical recommendations for diagnostic accuracy studies in low prevalence situations

Low disease prevalence poses challenges for diagnostic accuracy studies because of the large sample sizes that are required in order to obtain sufficient precision. The aim is to collate and discuss designs of diagnostic accuracy studies suited for use in low prevalence situations.

Source: Journal of Clinical Epidemiology - May 27, 2019 Category: Epidemiology Authors: Gea A. Holtman, Marjolein Y. Berger, Huibert Burger, Jonathan J. Deeks, Norbert Donner-Banzhoff, Thomas R. Fanshawe, Constantinos Koshiaris, Mariska M. Leeflang, Jason L. Oke, Rafael Perera, Johannes B. Reitsma, Ann Van den Bruel Tags: Review Source Type: research