Interaction effect of obstructive sleep apnea and periodic limb movements during sleep on heart rate variability.

Interaction effect of obstructive sleep apnea and periodic limb movements during sleep on heart rate variability. J Sleep Res. 2019 May 26;:e12861 Authors: Li X, Covassin N, Zhou J, Zhang Y, Ren R, Yang L, Tan L, Li T, Xue P, Tang X Abstract We aimed at assessing cardiac autonomic function by heart rate variability during sleep in patients with obstructive sleep apnea and periodic limb movements during sleep, and to compare it with that of patients with obstructive sleep apnea only, periodic limb movements during sleep only, and controls. We also aimed at investigating the interaction effect between apnea-hypopnea index and periodic limb movement index on heart rate variability. Four groups of patients (n = 42 each, total = 168) were identified based on the presence/absence of obstructive sleep apnea and periodic limb movements during sleep: + obstructive sleep apnea/- periodic limb movements during sleep (5 ≤ apnea-hypopnea index < 30 events per hr), - obstructive sleep apnea/+ periodic limb movements during sleep (periodic limb movement index > 15 events per hr), + obstructive sleep apnea/+ periodic limb movements during sleep, - obstructive sleep apnea/- periodic limb movements during sleep (controls). All groups were matched for age, sex and body mass index. Time- and frequency-domain heart rate variability measures were calculated over 5-min periods of stable stage 2 non-rapid eye m...
Source: Journal of Sleep Research - Category: Sleep Medicine Authors: Tags: J Sleep Res Source Type: research