Fertility Treatment Tied to Deadly Heart Problem in Pregnancy: Study

TUESDAY, May 28, 2019 -- The risk of a pregnancy-related type of heart failure is five times higher for women who undergo fertility treatment than those who conceive naturally, a new study says. The condition is called peripartum cardiomyopathy...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

Related Links:

The study shows that the risk of a particular kind of heart failure that happens in pregnancy, peripartum cardiomyopathy (PPCM), is five times higher in women who have fertility treatment,
Source: WebMD Health - Category: Consumer Health News Source Type: news
​BY JENNIFER TUONG; IVAN KHARCHENKO; JEAN LUC AGARD; &AHMED RAZIUDDIN, MDA 65-year-old man who had HIV well-controlled with highly active antiretroviral therapy, hypertension, sciatica, and restless leg syndrome presented to the emergency department with left leg pain. He also had had chemotherapy and radiation for anal cancer. The patient said the pain had started 45 minutes earlier when he was sitting on the toilet.He described the pain as sore in quality and 10/10 on the pain scale. He reported that it had started in his lower back and radiated to his left leg. He said he had had no trauma or weakness to the regio...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Abstract Anthracycline-associated cardiomyopathy and peripartum cardiomyopathy are nonischemic cardiomyopathies that often afflict previously healthy young patients; both diseases have been well described since at least the 1970s and both occur in the settings of predictable stressors (ie, cancer treatment and pregnancy). Despite this, the precise mechanisms and the ability to reliably predict who exactly will go on to develop cardiomyopathy and heart failure in the face of anthracycline exposure or childbirth have proven elusive. For both cardiomyopathies, recent advances in basic and molecular sciences have illu...
Source: Circulation Research - Category: Cardiology Authors: Tags: Circ Res Source Type: research
This study used a Danish cohort of women to investigate perinatal outcomes in women with prior PPCM.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mother, Fetus, Neonate Source Type: research
Diagnostic criteria for peripartum cardiomyopathy are: Development of heart failure in the last month of pregnancy or within 5 months after delivery Left ventricular systolic dysfunction with ejection fraction less than 45% No other identifiable cause for heart failure No recognized heart disease before the last month of pregnancy Reference van Spaendonck-Zwarts KY1, van Tintelen JP, van Veldhuisen DJ, van der Werf R, Jongbloed JD, Paulus WJ, Dooijes D, van den Berg MP. Peripartum cardiomyopathy as a part of familial dilated cardiomyopathy. Circulation. 2010 May 25;121(20):2169-75.
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Cardiology Source Type: blogs
ConclusionPreeclamptic women with risk factors for PPCM and women with pePPCM at increased risk of MACE should be followed closely. Further studies are required to determine whether preeclampsia affects the long-term prognosis of women with PPCM.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
This article, therefore, attempts to raise awareness among cardiac and obstetric anesthesiologists as well as intensivists of this often fatal diagnosis.This review summarizes theories of the pathophysiology and outcome of peripartum cardiomyopathy.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Review Article Source Type: research
Authors: Isogai T, Kamiya CA Abstract Peripartum cardiomyopathy (PPCM) is a specific cardiomyopathy in which heart failure develops due to reduced myocardial contraction during pregnancy or in the postpartum period in women without a previous history of heart disease. The epidemiology of PPCM has been reported in various countries and areas, and the incidence of PPCM differed among these reports. The incidence was highest (1 in 102 deliveries) in Nigeria and lowest (1 in 15,533 births) in Japan. The incidence was higher in African-Americans than in other races in several reports from the United States, and was also...
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research
Peripartum cardiomyopathy (PPCM) is a rare, but serious and potentially life-threatening condition. The nursing hormone Prolactin has been hypothesized as potential pathogenic factor of PPCM. Positive family history could be a reason for genetically caused peripartum heart failure that has possibly been demasked by the physiological pregnancy stress in a subset of patients. From animal models mutations in STAT3 may be involved in these genetic forms of PPCM.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 969 Source Type: research
Introduction: Peripartum cardiomyopathy (PPCM) is a rare but potentially life-threatening disease defined by idiopathic heart failure towards the end of pregnancy or up to six months after delivery. 6 –12 months recovery rates are 47–72% in recent cohorts, but data on longer term prognosis are few. PPCM is often preceded by preeclampsia and the two conditions share pathophysiological mechanisms including disturbed levels of the antiangiogenic factor soluble Fms-like tyrosine kinase (sFlt-1) a nd placental growth factor (PlGF).
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 10 – Obstetrics: Hypertension Source Type: research
More News: Cardiology | Cardiomyopathy | General Medicine | Heart | Heart Failure | Pregnancy | Reproduction Medicine | Study | Women