The impact of dose algorithms on tumor control probability in intensity-modulated proton therapy for breast cancer

Current proton therapy clinical practices primarily use the pencil-beam (PB) algorithm for dose calculations, as it has been the mainstay of commercially-available proton dose calculation algorithms and offers efficient treatment planning workflow. On the other hand, PB algorithms are known to be inaccurate in heterogeneous tissue environment or when a range shifter is used. To this end, Monte Carlo (MC) algorithm have recently been introduced into proton treatment planning systems that provide much more accurate dose modeling.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research