Bioenergetic aspects of archaeal and bacterial hydrogen metabolism.
Bioenergetic aspects of archaeal and bacterial hydrogen metabolism. Adv Microb Physiol. 2019;74:487-514 Authors: Pinske C Abstract Hydrogenases are metal-containing biocatalysts that reversibly convert protons and electrons to hydrogen gas. This reaction can contribute in different ways to the generation of the proton motive force (PMF) of a cell. One means of PMF generation involves reduction of protons on the inside of the cytoplasmic membrane, releasing H2 gas, which being without charge is freely diffusible across the cytoplasmic membrane, where it can be re-oxidized to release protons. A second route of PMF generation couples transfer of electrons derived from H2 oxidation to quinone reduction and concomitant proton uptake at the membrane-bound heme cofactor. This redox-loop mechanism, as originally formulated by Mitchell, requires a second, catalytically distinct, enzyme complex to re-oxidize quinol and release the protons outside the cell. A third way of generating PMF is also by electron transfer to quinones but on the outside of the membrane while directly drawing protons through the entire membrane. The cofactor-less membrane subunits involved are proposed to operate by a conformational mechanism (redox-linked proton pump). Finally, PMF can be generated through an electron bifurcation mechanism, whereby an exergonic reaction is tightly coupled with an endergonic reaction. In all cases the protons can be channelled back inside through a F1F0-ATP...
Conclusion: Based on these results NDDS is considered to be an applicable instrument for identifying personality pathology in patients with depressive symptoms, by recognizing the specific pattern. This is thought to be important for adequate treatment planning. PMID: 31517547 [PubMed - as supplied by publisher]
The conversations -- all with college students between 18 and 21 -- give anecdotal looks into how the nicotine-addicted are dealing with what officials have called a public health crisis.
A 10-year-old girl is fighting for her life after she contracted a brain-eating amoeba after swimming in the Brazos River and Lake Whitney in Bosque County near Waco, Texas.
Don't do it. Please don't do it.
WHEN celebrated artist Alison Lapper began making plans for her wedding, her dream was for her son Parys to give her away.
[And we've reached the 50th Anniversary of Revista Argentina de Microbiología]. Rev Argent Microbiol. 2019 Jul - Sep;51(3):189-190 Authors: Di Conza JA, Predari SC PMID: 31514958 [PubMed - in process]
I am a big fan of Prue Leith, 79, pictured, and have no doubt her knowledge of souffles is unsurpassed, I'm not sure if the same can be said of her medical experience, writes EVE SIMMONS.
PMID: 31514692 [PubMed - in process]
As a child born in 2018, my little girl has a one in three chance of living to 100. In contrast, as someone born in 1917, Pamela would have been considered lucky to live past 60.
CONCLUSIONS Our results demonstrated a regulation loop among MATAL1, miR-194, and YAP1, which dynamically regulates the progression of AP, providing a new therapeutic target for treatment of this disease. PMID: 31518341 [PubMed - in process]