Novel Mutations in KCNQ4, LHFPL5 and COCH Genes in Iranian Families with Hearing Impairment.

CONCLUSION: The 16% contribution of GJB2 to HL in the Iranian population necessitates the discovery of the remaining causal factors. This study is the first to report KCNQ4 and COCH related HL in the Iranian population and the second study, globally, to report HL due to biallelic inactivation of the COCH gene. PMID: 31126177 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31126177?dopt=Abstract

Source: Archives of Iranian Medicine - March 31, 2019 Category: Middle East Health Authors: Mehregan H, Mohseni M, Akbari M, Jalalvand K, Arzhangi S, Nikzat N, Kahrizi K, Najmabadi H Tags: Arch Iran Med Source Type: research