Cardiovascular Protection With Anti-Hyperglycemic Agents Cardiovascular Protection With Anti-Hyperglycemic Agents

Anti-hyperglycemic drugs are commonly used in the treatment of diabetes. Could certain agents provide cardiovascular benefits as well?American Journal of Cardiovascular Drugs
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

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Publication date: Available online 15 October 2019Source: Food Research InternationalAuthor(s): Mohammed Bule, Shekoufeh Nikfar, Mohsen Amini, Mohammad AbdollahiAbstractThymoquinone (2-isopropyl-5-methylbenzo-1, 4-quinone) (TQ) is a quinone derivative with a yellow crystalline appearance, abundantly found in black cumin, Nigella sativa L. TQ has diverse pharmacological properties. The aim of this systematic review on the antidiabetic effects of TQ is to evaluate the currently available evidence and conduct meta-analysis. A literature search of articles published until 25 January 2019 was done on PubMed, EMBASE, Web of Scie...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 9 October 2019Source: Food Research InternationalAuthor(s): Dave Jaydeep Pinakin, Vikas Kumar, Sheenam Suri, Rakesh Sharma, Manisha KaushalAbstractA numerous types of tree flowers are present in nature and few of them such as Rhdodendron, Bauhinia, Mahua, Gulmohar, Palash, Sesbania, Woodfordia, Simbal, etc. are being utilized traditionally as food and medicine by the localities of India. These flowers are rich in phytochemical (flavonoids, anthocyanins, phenolic acids, carotenoids, tannins, saponins) and possessing numerous health benefits (antioxidant activity, anti-inflammation, anti-ca...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 18 October 2019Source: Molecular and Biochemical ParasitologyAuthor(s): Felicity E. Lumb, Jenny Crowe, James Doonan, Colin J. Suckling, Colin Selman, Margaret M. Harnett, William HarnettAbstractOne of the most rapidly increasing human public health problems is obesity, whose sequelae like type-2 diabetes, represent continuously worsening, life-long conditions. Over the last 15 years, data have begun to emerge from human and more frequently, mouse studies, that support the idea that parasitic worm infection can protect against this condition. We have therefore investigated the potential of...
Source: Molecular and Biochemical Parasitology - Category: Parasitology Source Type: research
Publication date: Available online 18 October 2019Source: Journal of Molecular BiologyAuthor(s): Leticia P. Roma, Jean-Christophe JonasAbstractInsulin-secreting pancreatic β-cells play a critical role in blood glucose homeostasis and the development of type 2 diabetes (T2D) in the context of insulin resistance. Based on data obtained at the whole cell level using poorly specific chemical probes, reactive oxygen species (ROS) like superoxide and hydrogen peroxide have been proposed to contribute to the stimulation of insulin secretion by nutrients (positive role) and to the alterations of cell survival and secretory fu...
Source: Journal of Molecular Biology - Category: Molecular Biology Source Type: research
Publication date: Available online 18 October 2019Source: Life SciencesAuthor(s): Ricardo Beltrame de Oliveira, Valquiria Aparecida Matheus, Leandro Pereira Canuto, Ariane De Sant'ana, Carla Beatriz Collares-BuzatoAbstractAimHigh-fat diet (HFD) intake has been associated with changes in intestinal microbiota composition, increased intestinal permeability, and onset of type 2 diabetes mellitus (T2DM). The aim of this work was twofold: 1) to investigate the structural and functional alterations of the tight junction (TJ)-mediated intestinal epithelial barrier of ileum and colon, that concentrate most of the microbiota, after...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: May 2020Source: Value in Health Regional Issues, Volume 21Author(s): Xiaomeng Yue, Jiuhong Wu, Zhen Ruan, Michael L. Wolden, Lanting Li, Yong LinAbstractBackgroundHypoglycemia is a common acute complication in patients with diabetes and markedly impacts on medical resource use.ObjectivesTo make an initial assessment of the incidence of hypoglycemia and the associated utilization of medical resources and medical costs in insulin-treated patients with diabetes using medical records from 4 tertiary hospitals in China.MethodsA retrospective cohort study was conducted using electronic medical records from 4 te...
Source: Value in Health Regional Issues - Category: International Medicine & Public Health Source Type: research
Conclusions: PDO with neoprene-based glue is a safe technique that equalizes early outcome of selected patients at high risk of POPF to those at low risk undergoing PJA. Neoprene-based PDO, however, triples the risk of diabetes at 1 and 3 years.
Source: Annals of Surgery - Category: Surgery Tags: ESA PAPERS Source Type: research
Conclusion: Benchmark cutoffs targeting perioperative outcomes in BS offer a new tool in surgical quality-metrics and may be implemented in quality-improvement cycle. ClinicalTrials.gov Identifier NCT03440138
Source: Annals of Surgery - Category: Surgery Tags: ESA PAPERS Source Type: research
Conclusions Digital storytelling is an effective way to portray illness from a patient perspective, and the addition of this approach to pathophysiology instruction can benefit student learning.
Source: Nurse Educator - Category: Nursing Tags: Feature Articles Source Type: research
Background: In US cystic fibrosis (CF) patients, methicillin-resistant Staphylococcus aureus (MRSA) rates have tripled in the past 2 decades. Known clinical risk factors include exposure to a healthcare setting, Pseudomonas aeruginosa and CF-related diabetes. Area-level socio-environmental exposures have not been evaluated. We explored the association of area-level deprivation with MRSA prevalence in a pediatric CF Center in the Southeastern United States. Methods: Patients’ residential addresses were geocoded and linked to a composite Area Deprivation Index and Rural-Urban Commuting Area scores. The association...
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
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