Neural mechanisms of expectancy-based placebo effects in antidepressant clinical trials

ConclusionsResults from this study, the first designed to identify the neural mechanisms of expectancy augmentation in an antidepressant randomized control trial, suggest that therapeutic modulation of amygdala activity may be an important pathway by which patient outcome expectancy influences depressive symptoms.Clinicaltrials.gov identifierNCT01919216; Trial name: Placebo Effects in the Treatment of Depression: Cognitive and Neural Mechanisms, URL: https://clinicaltrials.gov/ct2/show/NCT01919216
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research