Ten-Year Average Full Follow-up and Evaluation of a Contoured Focal Resurface Prosthesis (HemiCAP) in Patients in the United Kingdom

J Knee Surg DOI: 10.1055/s-0039-1688921A significant number of patients are affected by localized articular damage that is appropriate neither for traditional arthroplasty nor for biological repair. A focal resurfacing system using a matched contoured articular prosthetic (HemiCAP) has been introduced for the treatment of such cases. Independent long-term results of these implants are limited. We retrospectively evaluated the use of this resurfacing system in 14 patients (13 males, 1 female), with a mean age of 40.3 years (range: 28–49), with focal femoral condyle defects. The same consultant orthopaedic surgeon performed all procedures. Our primary outcome measure was revision rate. Secondary outcome measures included radiographic evaluation (prosthesis migration signs, radiolucency), patient-reported functional evaluation (knee injury and osteoarthritis outcome scores), and complications. A total of 10 patients were treated on the medial femoral condyle, 2 were treated on the lateral condyle, and 2 received bicondylar implants (14 in total). Average follow-up was 107 months (range: 59–135). Three patients were lost to follow-up at the time of study. One patient was excluded from the study. Of the 10 left, 2 had to be revised, leading the survival rate to be 80% at 9.4 years. In four contactable patients, average Knee injury and Osteoarthritis Outcomes score at 121 months postsurgery (9.75 years) was 92.9 (as compared with 57.7 preoperatively). There were no comp...
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research

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ConclusionTwenty years after open rotator cuff repair, the rate of osteoarthritis was 29%. Massive rotator cuff tears were significantly associated with a higher rate of osteoarthritis. Less osteoarthritis was observed when suprasupinatus healed.Level of evidenceIV.
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
ConclusionAlthough meniscal repair theoretically may provide improvement in biomechanical loading, patients undergoing repair had higher complication rates than those undergoing partial meniscectomy. Clinicians should consider the available implants in determining which tear patterns to repair and future studies with long-term follow-up are needed to investigate complications (e.g. secondary meniscal procedures) as well as the potential for delay in the development of osteoarthritis.Level of evidenceLevel IV.
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
ConclusionOsteoarthritis patients have significantly elevated serum and synovial levels of midkine that were correlated with functional status assessed with WOMAC index and obviously associated with radiological progression on MSUS suggesting that it could be a useful marker to reflect OA severity and implies a possible role in the disease pathogenesis.
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
The objective of this Review is to describe the safety and efficacy of adipose stem/stromal cells (ASC) and stromal vascular fraction (SVF) in treating common diseases and the next steps in research that must occur prior to clinical use. Pubmed, Ovid Medline, Embase, Web of Science, and the Cochrane Library were searched for articles about use of SVF or ASC for disease therapy published between 2012 and 2017. One meta ‐analysis, 2 randomized controlled trials, and 16 case series were included, representing 844 human patients. Sixty‐nine studies were performed in preclinical models of disease. ASCs improved symptoms, fi...
Source: Stem Cells - Category: Stem Cells Authors: Tags: Regenerative Medicine Source Type: research
Publication date: May 2018Source: Arthroscopy Techniques, Volume 7, Issue 5Author(s): Somsak Kuptniratsaikul, Thun Itthipanichpong, Vanasiri KuptniratsaikulAbstractMedial meniscal root injury is known to cause an increase in tibiofemoral contact pressure and results in early osteoarthritis. There have been many reports on meniscal root repairing techniques, which can be categorized into 2 groups. One is transosseous suture, and the other is anchor suture repair. Both techniques show improvement in not only clinical performance, but also radiographic finding. However, the meniscal root repair procedure must be performed by ...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
ConclusionThe physiologic and hormonal changes during pregnancy leading to increased ligamentous laxity may put vulnerable patients with hip dysplasia and iatrogenic instability at increased risk for progression of osteoarthritis.
Source: Journal of Orthopaedics - Category: Orthopaedics Source Type: research
Publication date: May 2018Source: Arthroscopy Techniques, Volume 7, Issue 5Author(s): Somsak Kuptniratsaikul, Thun Itthipanichpong, Vanasiri KuptniratsaikulAbstractMedial meniscal root injury is known to cause an increase in tibiofemoral contact pressure and results in early osteoarthritis. There have been many reports on meniscal root repairing techniques, which can be categorized into 2 groups. One is transosseous suture, and the other is anchor suture repair. Both techniques show improvement in not only clinical performance, but also radiographic finding. However, the meniscal root repair procedure must be performed by ...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
ConclusionThe physiologic and hormonal changes during pregnancy leading to increased ligamentous laxity may put vulnerable patients with hip dysplasia and iatrogenic instability at increased risk for progression of osteoarthritis.
Source: Journal of Orthopaedics - Category: Orthopaedics Source Type: research
ConclusionThis study did not demonstrate coherent statistical differences between both cartilage repair procedures. MFX might be superior in the treatment of small cartilage defects.
Source: International Orthopaedics - Category: Orthopaedics Source Type: research
CJ Abstract Background and purpose - The optimal treatment for traumatic cartilage injuries remains unknown. Contrast-enhanced MRI of cartilage (dGEMRIC) evaluates cartilage quality and a low dGEMRIC index may predict radiographic osteoarthritis (OA). The purpose of this study was (a) to explore the results 17 years after surgical treatment of an isolated cartilage knee injury and (b) to evaluate the predictive value of dGEMRIC. Patients and methods - 16 knees with an isolated traumatic cartilage injury of the medial femoral condyle had cartilage repair surgery either by microfracture or autologous cartilage impl...
Source: Acta Orthopaedica - Category: Orthopaedics Authors: Tags: Acta Orthop Source Type: research
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