Data Show that Federal Investment in Research Pays Dividends

In 1990, the federal government formally launched an ambitious initiative to sequence the human genome, to identify all the genes in human DNA, and to develop the tools to store and allow access to this information. The effort took 13 years and cost the federal government $3.8 billion. As is evidenced by technological advancements, the cultivation of new lines of research, and countless subsequent scientific discoveries, the Human Genome Project (HGP) was a success by nearly all measures. A question of interest to policymakers, however, is what the economic return on this kind of federal investment is. The HGP generated great prosperity, according to a 2011 report by the Battelle Technology Partnership Practice. Between 1988 and 2010, human genome sequencing and associated activities by private industry and researchers generated $796 billion in US economic output. This represents a return on investment of $141 for every $1 spent by the government. The HGP has also generated an estimated 3.8 million job-years of employment and increased government revenue. As was reported by the Battelle group, the genomics-enabled industry generated more than $3.7 billion in federal taxes and $2.3 billion in state and local taxes in 2010 alone. "Thus in one year, revenues returned to government nearly equaled the entire 13-year investment in the HGP," states the report. Beyond economic benefits, the HGP has influenced and benefited numerous disciplines outside genomics. From human h...
Source: Washington Watch - Category: Biology Authors: Source Type: news

Related Links:

Publication date: Available online 7 December 2019Source: Saudi Pharmaceutical JournalAuthor(s): Kinga OstrowskaAbstractA number of psychiatric disorders, including anxiety, schizophrenia, Parkinson’s disease, depression and others CNS diseases are known to induce defects in the function of neural pathways sustained by the neurotransmitters, like dopamine and serotonin. N-arylpiperazine moiety is important for CNS-activity, particularly for serotonergic and dopaminergic activity. In the scientific literature there are many examples of coumarin-piperazine derivatives, particularly with arylpiperazines linked to a coum...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Functional coupling of M1 muscarinic acetylcholine receptor to Gαq/11 in dorsolateral prefrontal cortex from patients with psychiatric disorders: a postmortem study. Eur Arch Psychiatry Clin Neurosci. 2019 Dec 05;: Authors: Odagaki Y, Kinoshita M, Meana JJ, Callado LF, García-Sevilla JA Abstract Accumulating studies have implicated intracellular signaling through muscarinic acetylcholine receptors (mAChRs) in psychiatric illness. In the present study, carbamylcholine chloride (carbachol)-induced Gαi/o and Gαq/11 activation was identified in postmortem human prefrontal cortical ...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
CONCLUSIONS: Prenatally initiated CBT did not improve maternal symptoms or child outcomes among non-help-seeking women with antenatal depression or anxiety. Our findings are not in line with present recommendations for universal screening and treatment for antenatal depression or anxiety, and future work may include the relevance of baseline help-seeking. PMID: 31806071 [PubMed - as supplied by publisher]
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
Physician burnout can be a contributing factor to depression, substance abuse, problems with relationships, and thoughts of suicide. Burnout of physicians also results in decreased quality, safety, and outcomes for patients and more financial costs for health-care institutions. It is not enough for health-care systems to focus on helping the individual; these organizations also need to understand that they are the main cause of physician burnout and take appropriate action to reform their processes.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: From the American College of Nuclear Medicine Source Type: research
Publication date: Available online 6 December 2019Source: Psychiatric Clinics of North AmericaAuthor(s): Gabriele Sani, Alan C. Swann
Source: Psychiatric Clinics of North America - Category: Psychiatry Source Type: research
ConclusionsRumination is known to be associated with poor prognosis in mental health. This study suggests that rumination is a maladaptive coping style associated not only with worry, distress and illness severity, but also with socioeconomic status. Also, rumination demonstrated a specific association with panic disorder.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
ConclusionsSA can be predicted significantly from pre-deployment data, but intervention planning needs to take PPV into consideration.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 6 December 2019Source: Journal of Psychiatric ResearchAuthor(s): Anthony J. Rosellini, Siyu Liu, Grace N. Anderson, Sophia Sbi, Esther Tung, Evdokia KnyazhanskayaAbstractA growing literature is utilizing machine learning methods to develop psychopathology risk algorithms that can be used to inform preventive intervention. However, efforts to develop algorithms for internalizing disorder onset have been limited. The goal of this study was to utilize prospective survey data and ensemble machine learning to develop algorithms predicting adult onset internalizing disorders. The data were from...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 7 December 2019Source: Journal of Anxiety DisordersAuthor(s): David H. Rosmarin, Steven PirutinskyAbstractReligion is professed by the majority of the general population, but a minority of mental health practitioners. We evaluated whether religious patients benefited more from treatment with religious psychotherapists in a naturalistic study among adult Orthodox Jewish (n = 117) and control patients (n = 91) receiving psychotherapy from Orthodox Jewish (n = 15) and other (n = 7) psychotherapists at a New York based outpatient clinic....
Source: Journal of Anxiety Disorders - Category: Psychiatry Source Type: research
Publication date: Available online 7 December 2019Source: Progress in NeurobiologyAuthor(s): M.M.J. van den Berg, J. Krauskopf, J.G. Ramaekers, J.C.S. Kleinjans, J. Prickaerts, J.J. BriedéAbstractCirculating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as promising biomarkers for central nervous system (CNS) disorders because they are actively secreted as messengers and are profoundly involved in fine-tuning of developmental and differentiation processes. Furthermore, they are attractive biomarkers becau...
Source: Progress in Neurobiology - Category: Neuroscience Source Type: research
More News: Biology | Depression | Economic Slowdown | Employment | Environmental Health | Forensic Medicine | Funding | Genetics | Government | Health | Jobs | Partnerships | Recession | Science | Tax