Tumor microenvironmental growth factors induce long-term estrogen deprivation resistance in breast cancer.

CONCLUSIONS: This study demonstrates the importance of tumor microenvironment-derived factors for the development of AI resistance. These resistant models did not utilize the same resistance mechanism, suggesting that flexible strategies are essential in conquering resistance. PMID: 31119683 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31119683?dopt=Abstract

Source: Breast Cancer - May 21, 2019 Category: Cancer & Oncology Authors: Tsuboi K, Uematsu C, Yamaguchi Y, Niwa T, Hayashi SI Tags: Breast Cancer Source Type: research