King of the Queen City: The Urologist Who Saved Buffalo

When thinking of the great men and women of urology, one might consider the early pioneers in treatment of stones, voiding dysfunction, infertility, or cancer. Throughout history, urologists have also been technological leaders and have been at the cutting edge of medicine and public health. One such leader, Walter D. Greene, emerged in the “Queen City” of Buffalo, New York at the turn of the 20th century, when one of the most serious issues facing American cities was the outbreak of venereal and infectious diseases.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research

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Publication date: Available online 15 June 2019Source: MethodsAuthor(s): Rui Yan, Fei Ren, Zihao Wang, Lihua Wang, Tong Zhang, Yudong Liu, Xiaosong Rao, Chunhou Zheng, Fa ZhangAbstractEven with the rapid advances in medical sciences, histopathological diagnosis is still considered the gold standard in diagnosing cancer. However, the complexity of histopathological images and the dramatic increase in workload make this task time consuming, and the results may be subject to pathologist subjectivity. Therefore, the development of automatic and precise histopathological image analysis methods is essential for the field. In thi...
Source: Methods - Category: Molecular Biology Source Type: research
Publication date: Available online 15 June 2019Source: Journal of Molecular LiquidsAuthor(s): Prakash Bansode, Pradnya Patil, Prafulla Choudhari, Manish Bhatia, Apurva Birajdar, Indumathi Somasundaram, Gajanan RashinkarAbstractA novel series of ferrocene tethered ionic liquids (ILs) has been synthesized by quaternization of 1-N-(ferrocenylmethyl)benzimidazole, 1-N-(ferrocenylmethyl)imidazole and 1-N-(ferrocenylmethyl)-1,2,4-triazole with long chain alkyl bromides. The synthesized ILs were screened for their anticancer activity against human breast cancer cell line MCF-7. ILs 2a–d and 4b displayed significant anticanc...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
In this study, whole genome comparative genomic hybridization array (array CGH) based genomic analysis was performed on twelve Saudi Lynch syndrome patients. A total of 124 chromosomal alterations (structural loss) were identified at mean log2 ratio cut off value of ±0.25. We also found structural loss in 2p21-p16.3, 3p23-p14.2, 7p22.1 and 1p34.1-p33 regions. These findings were subsequently validated by real time quantitative PCR showing downregulation of MSH2, MSH6, EPCAM, MLH1, PMS2 and MUTYH genes. These findings shall help in establishing database for alterations in mismatch repair genes underlying Lynch syndro...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Chammari Pothipor, Natta Wiriyakun, Thitirat Putnin, Aroonsri Ngamaroonchote, Jaroon Jakmunee, Kontad Ounnunkad, Rawiwan Laocharoensuk, Noppadol AroonyadetAbstractRecent studies show that electrochemical biosensors offer simple, robust and low-cost solution for point-of-care applications. To meet rigorous requirements of early disease diagnosis and other medical applications, nanomaterials have been investigated to increase sensitivity and selectivity of electrochemical sensors. Herein, we successfully developed graphene-poly(3-...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Abstract The underlying molecular basis for neurodevelopmental or neuropsychiatric disorders is not known. In contrast, mechanistic understanding of other brain disorders including neurodegeneration has advanced considerably. Yet, these do not approach the knowledge accrued for many cancers with precision therapeutics acting on well-characterized targets. Although the identification of genes responsible for neurodevelopmental and neuropsychiatric disorders remains a major obstacle, the few causally associated genes are ripe for discovery by focusing efforts to dissect their mechanisms. Here, we make a case for del...
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Tags: CNS Neurosci Ther Source Type: research
Authors: Albisinni S, Pretot D, Al Hajj Obeid W, Aoun F, Quackels T, Peltier A, Roumeguère T Abstract INTRODUCTION: The neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) are established markers of systemic inflammation. Moreover, anemia is a known adverse prognostic factor and reduced haemoglobin to platelet ratio (HPR) seems associate to poor outcomes in urothelial cancer. Aim of the current study was to explore the prognostic value of NLR, HPR and PLR in patients harboring localized RCC. Materials and Methods 184 patients undergoing partial and radical nephrectomy for renal ma...
Source: Progres en Urologie - Category: Urology & Nephrology Tags: Prog Urol Source Type: research
Women having trouble getting pregnant sometimes try yoga, meditation or mindfulness, and some research suggests that psychological stress may affect infertility. But what about men: Does their mental state affect a couple's ability to conceive? The latest research on this subject was published Thursday in the journal Fertility and Sterility and suggests that a link between mental health […]Related:CDC comes close to an all-clear on romaine lettuce as E. coli outbreak nears historic levelSurrogate mothers ask Supreme Court to stop ‘exploitation’ of women and babiesMore men with low-risk pro...
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news
Women having trouble getting pregnant sometimes try yoga, meditation or mindfulness, and some research suggests that psychological stress may affect infertility. But what about men: Does their mental state affect a couple's ability to conceive? The latest research on this subject was published Thursday in the journal Fertility and Sterility and suggests that a link between mental health […]Related:CDC comes close to an all-clear on romaine lettuce as E. coli outbreak nears historic levelSurrogate mothers ask Supreme Court to stop ‘exploitation’ of women and babiesMore men with low-risk pro...
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
The HPV vaccine has proven to be a disaster. This vaccine, developed to protect young women from cervical cancer, has failed to provide protection. In fact, it has succeeded in doing the opposite by increasing cervical cancer rates in those vaccinated. Reports of health damage caused by this vaccine are immense. The HPV vaccination has been linked with life-threatening autoimmune disorders, cancer, paralysis, infertility and death. In fact, several countries have opposed the vaccine, as evidenced through public warning or lawsuits. A lead researcher of the vaccine has advised parents not to use it. One independent group of...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Logical Michelle Goldstein Recent Articles American Medical Association (AMA) autoimmune disorders blood clots brain inflammation Centers for Disease Control (CDC) Cervarix disabling fatigue eizures facial paralysis gardasil Guil Source Type: blogs
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