EGCG, a green tea polyphenol, as one more weapon in the arsenal to fight radiation esophagitis?

Radiotherapy (RT) is a mainstay in the treatment of locally advanced non-small cell lung cancer (NSCLC). The addition of chemotherapy (CHT) to RT improves the survival of patients with NSCLC [1]. A concurrent approach is superior to a sequential CHT-RT approach in patients with PS 0 –1 and stage III NSCLC [2]. If, for any reason, CHT cannot be given to such patients, the hyperfractionated acceleration of RT improves the treatment outcome compared with conventional fractionation [3]. However, these more efficacious treatment modalities are also more aggressive, i.e., more toxi c.

Source: Radiotherapy and Oncology - May 23, 2019 Category: Radiology Authors: Lucyna K ępka, Anna Rychter Tags: Editorial Source Type: research