The FTO Gene and Measured Food Intake in 5- to 10-Year-Old Children Without Obesity.

CONCLUSIONS: Results corroborate and extend prior work by showing a dose-dependent effect on food intake in children without obesity. PMID: 31119882 [PubMed - in process]
Source: Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Obesity (Silver Spring) Source Type: research

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ConclusionsCB1R was widely distributed in multiple hypothalamic nuclei. The expression of CB1R was augmented only when mice were treated with HFD and nicotine in combination. These data suggest that the exposure to nicotine may provoke an enhanced endocannabinoid response in diet-induced obesity.Graphical abstract
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
ConclusionsWith the application of a dual model, there appears to be no significant difference in mortality of obese patients with pneumonia compared to normal BMI patients with pneumonia.
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
Publication date: Available online 18 October 2019Source: Journal of Experimental Child PsychologyAuthor(s): Veronica Guardabassi, Carlo TomasettoAbstractThe high prevalence of childhood obesity has drawn increasing attention to the neurocognitive impairments associated with excess weight, and evidence has accumulated of a progressive decline in working memory at increasing levels of children’s Body Mass Index (BMI). However, obesity is also a highly stigmatizing condition, and pervasive societal stereotypes depict individuals with obesity as less intelligent than those with average weight. For this reason, we invest...
Source: Journal of Experimental Child Psychology - Category: Child Development Source Type: research
This study evaluates the effects of a chemically characterized polyphenolic extract of H. sabdariffa (HSE) in an experimental model of diet-induced obesity (DIO) in mice. HSE was administered daily by oral gave for 42 days. HSE reduced weight increase in high fat diet (HFD)-fed mice, and improved glucose tolerance, insulin sensitivity and normalized LDL/HDL cholesterol ratio. It also enhanced the inflammatory state in the liver, reducing the expression of different adipokines and proinflammatory mediators, and reinforced gut integrity by increasing the expression of mucins and proteins involved in the maintenance of mucosa...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 18 October 2019Source: Molecular and Biochemical ParasitologyAuthor(s): Felicity E. Lumb, Jenny Crowe, James Doonan, Colin J. Suckling, Colin Selman, Margaret M. Harnett, William HarnettAbstractOne of the most rapidly increasing human public health problems is obesity, whose sequelae like type-2 diabetes, represent continuously worsening, life-long conditions. Over the last 15 years, data have begun to emerge from human and more frequently, mouse studies, that support the idea that parasitic worm infection can protect against this condition. We have therefore investigated the potential of...
Source: Molecular and Biochemical Parasitology - Category: Parasitology Source Type: research
Publication date: Available online 18 October 2019Source: Physiology &BehaviorAuthor(s): Darryl A. Gaudet, Dalia El-Desoky, Jonquil M. Poret, H. Douglas Braymer, Stefany D. PrimeauxAbstractFood intake patterns are regulated by signals from the gustatory neural circuit, a complex neural network that begins at the tongue and continues to homeostatic and hedonic brain regions involved in eating behavior. The goal of the current study was to investigate the short-term effects of continuous access to a high fat diet (HFD) versus limited access to dietary fat on the gustatory neural circuit. Male Sprague-Dawley rats were fed...
Source: Physiology and Behavior - Category: Physiology Source Type: research
Publication date: Available online 18 October 2019Source: Journal of Vascular Surgery: Venous and Lymphatic DisordersAuthor(s): Côme Roux, Béatrice Villemur, Brigitte Giovannoni, Lucie Koeyemelk, Monique Mendelson, Meriem Benmerad, Marie Joyeux-Faure, Renaud Tamisier, Jean-Louis PepinAbstractObjectiveObstructive sleep apnea (OSA) syndrome is one of the most frequent chronic diseases in the general population. The nocturnal rostral fluid shift is accepted as a key mechanism in OSA pathogenesis in medical conditions associated with fluid overload. The main objective of this study was to assess the prevalence of ...
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
Our world is amidst a crucial overweight and obesity pandemic that continues to grow, with 2 billion of the world ’s population overweight and approximately 700 million adults with obesity.1 Once thought to be a disease of the rich and affluent, weight-related and metabolic diseases are on the rise across all socioeconomic classes and residential settings. The enduring physiologic and hormonal changes that oc cur with weight gain make sustainable weight loss with just diet and exercise, commonly known as lifestyle modification, not feasible for most people.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
In this study, we explored the effect of β -Lapachone ( β L), a compound obtained from the bark of the lapacho tree, against obesity. In vivo administration of β L into either high fat diet (HFD)-induced obese C57BL6 mice and genetically obese Lepr -∕- mice prevented body weight gain, which was associated with tissue weight loss of white adipose tissue (WAT). In addition, β L elevated thermogenic proteins including uncoupling protein 1 (UCP1) and mitochondrial count in BAT and human adipose tissue-derived mesenchymal stem cells (hAMSCs). β L also induced AMP-activated protein kinase (AMPK) phosph...
Source: The American Journal of Chinese Medicine - Category: Complementary Medicine Authors: Tags: Am J Chin Med Source Type: research
In conclusion, yacon syrup has a postprandial decreasing effect glucose and insulin concentrations in adult women. This effect was not evident for triglyceride concentration.Clinical trial registry: RBR-33wf46. Available in: abstract
Source: Food Research International - Category: Food Science Source Type: research
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