Suo Quan Wan Protects Mouse From Early Diabetic Bladder Dysfunction by Mediating Motor Protein Myosin Va and Transporter Protein SLC17A9
CONCLUSIONS: T2DM mice exhibited the early phase of diabetic bladder dysfunction (DBD) characterized by OAB and bladder dysfunction. SQW can improve the bladder storage and micturition of DBD mice by mediating the protein and gene expression levels of myosin Va and SLC17A9 in the bladder, instead of improving the blood glucose level.
There is evidence that an ancient Chinese form of martial arts improves your mind and body, and may even contribute to a longer life.
More than a third of patients with diabetes don't take their drugs as prescribed, sometimes because of cost concerns.
In conclusion, the therapeutic use of phytocannabinoids (CBD) is already in practice, although its mechanisms of action remain unclear. Endocannabinoid and TRPV1 mechanisms warrant further basic studies to support their potential clinical applications.This article is part of the Special Issue “NEWroscience 2018".
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Helena Hui Wang, Richard Horton
ConclusionThe present study reports a variant subgroup GII-a PEDV HM2017 strain in China and characterize its pathogenicity. PEDV strain HM2017 of subgroup GII-a presents a promising vaccine candidate for the control of PED outbreaks in China.
Publication date: Available online 12 December 2019Source: American Journal of Infection ControlAuthor(s): Jiancong Wang, Mouqing Zhou, Fangfei Liu
Authors: Tanik N, Tanik S, Albayrak S, Zengin K, Inan LE, Caglayan EK, Celikbilek A, Kirboga K, Gurdal M Abstract PURPOSE: Diabetes mellitus (DM) is a chronic metabolic disorder that often leads to complications. We aimed to correlate two complications of DM, polyneuropathy and hyperactive bladder syndrome, using noninvasive measures, such as screening tests. METHODS: We included 80 female and 40 male type 2 diabetic patients in this prospective study. Diabetic polyneuropathy evaluations were conducted using the Douleur Neuropathique 4 Questions (DN4), and overactive bladder (OAB) evaluations were performed usi...
Conclusions The presence of nocturia was associated with erectile dysfunction, systemic vascular events, higher mortality, and indicated poor health in male with type 2 diabetic mellitus.
W. J. Bang, J. Y. Lee, K. C. Koo, Y. S. Hah, D. H. Lee and K. S. Cho
ObjectivesTo explore whether serum and urinary advanced glycation end‐products (AGEs) are related to urinary symptoms and bladder dysfunctions in diabetic patients. MethodsForty‐seven patients with type 2 Diabetes mellitus (T2DM) and lower urinary tract symptoms (LUTS) were enrolled. LUTS evaluation was performed by IPSS (International Prostatic Symptoms Score), QoL (quality of life), OAB (overactive bladder). ICI‐SF (International Consultation on Incontinence – short form) quaestionneires; ultrasound examination, evaluation of postvoid residual (PVR), uroflowmetry, cystometry with pressure‐flow stu...