Effects of the selective estrogen receptor modulators for the treatment of male infertility: a systematic review and meta-analysis.

Conclusions: The results of this meta-analysis suggest that SERMs may be effective in the treatment of infertile patients with idiopathic infertility. However, the paucity of data does not allow to draw a definitive conclusion. PMID: 31120775 [PubMed - as supplied by publisher]
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research

Related Links:

ConclusionWhile components of a mixture of lipids and lipophilic micronutrients were associated with live birth outcomes following IVF, a larger investigation is necessary to fully evaluate the potential clinical implications.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Authors: Mencaglia L, Cerboneschi M, Ciociola F, Ricci S, Mancioppi I, Ambrosino V, Ferrandi C, Strozzi F, Piffanelli P, Grasselli A Abstract Female fertility plays a decisive role in the reproduction of mammals, with related issues that include oocyte or embryo quality, establishment of pregnancy, and the physiology of the tissues that contribute to reproduction and metabolic disorders associated with reproductive failure. Although reproductive failure may be attributed to various factors in different species, female infertility is largely controlled by a number of molecular signals that can be regulated in a cycl...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
AbstractPurpose of ReviewThe classification of morphologically normal sperm has been progressively redefined. Concurrently, our understanding of the significance of sperm morphology in relation to male factor infertility has evolved. In this review, we will discuss the evolution of sperm morphology assessment and factors that contribute to its measurement variability. We will examine the impact of sperm morphology on natural pregnancy, IUI, IVF, and ICSI outcomes.Recent FindingsThere is a lack of consensus on sperm morphology classification, technique, and inter-observer grading variability. Current evidence suggests sperm...
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research
With Father’s Day mere days away, we’re hearing more advertisements for outdoor grills and golf clubs, sailboats and fishing gear. As an infertility counselor, I am glad that Father’s Day is not welcomed with the gush of sentiment that envelops Mother’s Day. Still, a day dedicated to celebrating fatherhood can be difficult for any number of people. Among them are men and women who lost their fathers when they were quite young, and those who have experienced rocky relationships with their dads. There are men who have regrets about their own role as fathers, and older gay men who missed out on fatherh...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Fertility Infertility Men's Health Mental Health Relationships Source Type: blogs
About 13 out of every 100 couples cannot get pregnant. It's a stressful and emotional time, and it's often considered a female issue. The CDC says both men and women contribute to infertility in about 35 percent of couples. The man is the only factor in about eight percent of cases. Dr. Tara Narula joins "CBS This Morning" to discuss some of the causes of male infertility and why it's so difficult for men to talk about the issue.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Conditions:   Infertility;   Aneuploidy Intervention:   Procedure: Laser Acupuncture Sponsor:   University of British Columbia Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractObjectiveTo determine whether younger oocyte donor age is associated with better outcomes after in vitro fertilization (IVF) compared with older oocyte donor age.DesignA retrospective cohort study.SettingLarge academically affiliated infertility treatment center.PatientsWe included all women ≥ 18 years who started their first fresh cycle using donor oocytes at our center from January 2002 through October 2017; only the first oocyte recipient cycle was analyzed.InterventionLog-binomial regression was used to compare the incidence of clinical pregnancy and live birth among the following donor age groups:
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
Publication date: Available online 7 June 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Boughizane Sassi, Bannour Badra, Rjiba Ghada, Bannour Imen, El Abed Meriem, Khairi Hedi
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
CONCLUSION: There was no significant difference in clinical pregnancy rates when urinary LH and hCG trigger as methods to time insemination were compared in women undergoing gonadotropin stimulated IUI. This article is protected by copyright. All rights reserved. PMID: 31169952 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: BJOG Source Type: research
This study investigated whether retinoic acid (RA) may regulate the proteins that are essential for integrity of the BTB in cryptorchidism. Female Sprague-Dawley rats were administrated flutamide during late pregnancy to induce a model of cryptorchidism in male offspring. The concentrations of RA and BTB tight and gap junction protein levels were significantly lower in untreated cryptorchid pups compared with normal pups, but almost normal in cryptorchid pups given RA. Studies in vitro corroborated these findings. The sperm quality of RA-treated model pups was better compared with the untreated model. RA treatment may have...
Source: Reproductive Toxicology - Category: Toxicology Source Type: research
More News: Drugs & Pharmacology | Hormones | Infertility | Pregnancy | Reproduction Medicine | Study