Staphylococcus aureus responds to allicin by global S-thioallylation - Role of the Brx/BSH/YpdA pathway and the disulfide reductase MerA to overcome allicin stress.

In conclusion, allicin results in an oxidative shift of EBSH and protein S-thioallylation, which can be reversed by YpdA and the Brx/BSH/YpdA electron pathways in S. aureus to regenerate thiol homeostasis. PMID: 31121222 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31121222?dopt=Abstract

Source: Free Radical Biology and Medicine - May 19, 2019 Category: Biology Authors: Van Loi V, Thu Huyen NT, Busche T, Tung QN, Horst Gruhlke MC, Kalinowski J, Bernhardt J, Slusarenko A, Antelmann H Tags: Free Radic Biol Med Source Type: research