UC Davis researcher looks to cannabis compound to treat developmental disorders

Dr. Randi Hagerman is on the front lines of developing new treatments for kids with autism, Down syndrome and other developmental disorders.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news

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This study aims to fill gaps in the literature by describing developmental and behavioral phenotypes in this group relative to those with DS or ASD in isolation. Methods: Participants included 173 children (Mage = 73 months) with ASD, DS, or DS + ASD. Two 3 × 2 repeated-measures analyses of variance were completed with between-subject factors of the diagnostic group (DS, ASD, and DS + ASD) and within-subject factors of cognitive performance (verbal and nonverbal developmental quotient [DQ]) or ASD symptoms (social affect [SA] and restricted and repetitive behaviors [RRBs]). Results: Significant group-by-scale i...
Source: Journal of Developmental and Behavioral Pediatrics - Category: Child Development Tags: Original Article Source Type: research
Abstract Volunteer activities can provide opportunities to learn new skills, build social networks, and contribute to enhanced self-esteem. Volunteering also provides a positive contribution to society, and an opportunity to participate in activities that may differ from those in paid employment. People with severe disabilities and complex communication needs, however, may face significant barriers in participating and communicating in volunteer activities. A multiple-probe-across-participants, single-case experimental design was used to evaluate the effectiveness of videos with integrated visual scene displays (v...
Source: Augmentative and Alternative Communication - Category: Speech-Language Pathology Authors: Tags: Augment Altern Commun Source Type: research
Source: Developmental Neuropsychology - Category: Neurology Authors: Source Type: research
Abstract The modulation of the microbiota-gut-brain axis with a view to preventing and treating brain disorders became recently a hot topic for the scientific community. Dietary polyphenols are multifaceted compounds that have demonstrated to be highly advantageous to counteract inflammation, oxidative stress, and neurodegeneration, among other pathological conditions, being useful in the prevention and treatment of several chronic disorders. The potential of these compounds to prevent and treat brain disorders has not been only related to their capacity to reach the brain, depending on their chemical structure, a...
Source: Advances in Food and Nutrition Research - Category: Nutrition Authors: Tags: Adv Food Nutr Res Source Type: research
By guest blogger Dan Carney One of the most well-known psychological biases is the Dunning-Kruger effect: the tendency for individuals less skilled or knowledgeable in a particular area to overestimate their own performance. Now, a team of researchers from Miami University, Ohio, have offered the most robust evidence yet that this may apply to knowledge about autism — that what people think they know about the condition may not be that closely related to what they actually know. Writing in the March issue of Research in Autism Spectrum Disorders, the authors — led by Camilla McMahon — measured perce...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Autism guest blogger Source Type: blogs
ConclusionsOur results indicate the prevalence of multiple comorbidities varies across the lifespan in DS, and in adults, rates for psychiatric comorbidities show different patterns for males and females relative to expected population rates. Further, most health comorbidities are not associated with poorer cognitive outcomes in DS, apart from autism and epilepsy. It is essential for clinicians to consider such differences to provide appropriate care and treatment for those with DS and to provide prognostic information relating to cognitive outcomes in those with comorbidities.
Source: Journal of Neurodevelopmental Disorders - Category: Neurology Source Type: research
CONCLUSION: Intellectually disabled persons can be treated in a multimodal, multiprofessional approach. As of early 2019, there were 38 medical centers for adults with intellectual disability or severe multiple disabilities in Germany (Medizinische Behandlungszentren für Erwachsene mit geistiger Behinderung oder schweren Mehrfachbehinderungen, MZEB), where they can be cared for with due attention to their special needs. PMID: 31888794 [PubMed - in process]
Source: Deutsches Arzteblatt International - Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
AbstractSleep problems are common among children with neurodevelopmental disorders (NDDs). We review sleep disturbance in three major NDDs: autism spectrum disorder, Down syndrome, and fetal alcohol spectrum disorder (FASD). We review associations with functional impairment, discuss how patterns of sleep disturbance inform understanding of etiology, and theorize about mechanisms of impairment. Sleep disturbance is a transdiagnostic feature of NDDs. Caregivers report high rates of sleep problems, including difficulty falling or staying asleep. Polysomnography data reveal differences in sleep architecture and increased rates...
Source: Review Journal of Autism and Developmental Disorders - Category: Child Development Source Type: research
Publication date: January 2020Source: Research in Developmental Disabilities, Volume 96Author(s): Zachary Rossetti, Chung eun Lee, Meghan Burke, Sarah HallAbstractMost siblings of individuals with intellectual and developmental disabilities (IDD) report positive sibling relationships. However, extant research often only examines the perspective of the nondisabled sibling; it is unclear whether siblings with IDD report close sibling relationships. Thus, the aim of this study was to understand adult sibling relationships from the perspectives of both siblings with and without IDD. Using dyadic interviews, we examined the per...
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
(I copiedthis over from my shares feed as it fits better here).My #1 is doing their special Olympics strength training atBuilt on Bravery, located at the Mendota Height MN Lions United Fitness Center (map):Lions United is a new kind of training center, designed specifically to prepare people with disabilities for exceptional performance in individual competitions, team sports and life, especially people with autism, down syndrome and cerebral palsy. We ’re dedicated to Special Olympics’ Project UNIFY and Unified Sports®, which means we bring people of all abilities together to strengthen individua...
Source: Be the Best You can Be - Category: Disability Tags: athletics cognitive impairment exercise Explosive Child health Twin Cities Source Type: blogs
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