Clinical and Biochemical Phenotype of Adolescent Males with Gynecomastia

Conclusions: The E2/TTE ratio may be a helpful tool in diagnosing gynecomastia. Altered E2/TTE ratio might be responsible for part of cases described previously as idiopathic. Additionally, weight loss does not imply reduction of breast size in boys, nonetheless it should be the first step before further treatment of prolonged gynecomastia. PMID: 31117335 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research

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Authors: Rojas AP, Vo DV, Mwangi L, Rehman S, Peiris AN Abstract Klinefelter syndrome (47,XXY) has a prevalence of approximately 1 in 500 males. It is a condition characterized by an extra X chromosome and is an underdiagnosed clinical entity. Inactivation of genes enables their escape from regulatory mechanisms, which can result in such classic physical manifestations as hypogonadism, gynecomastia, infertility, and various hormonal and physical abnormalities. While the endocrine manifestations of 47,XXY are well-known, the oncologic manifestations have received less attention. An association between cancer and 47,...
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
This study examines the frequency of complications in adolescents following gynecomastia repair and measures their impact on patients’ postoperative HRQoL.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Breast Source Type: research
Gynecomastia, the benign proliferation of male glandular breast tissue, occurs in up to 80% of adolescents. Most cases are idiopathic and resolve without intervention; persistent cases (>3 years) are often treated with surgical resection. However, before proceeding with operative intervention, pediatricians and surgeons must: 1) screen for conditions that mimic gynecomastia, and 2) rule out causes of secondary gynecomastia. The purpose of this study is to develop a diagnostic algorithm for male adolescent breast hypertrophy.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Breast Source Type: research
Posaconazole therapy may lead to increased serum estradiol levels and development of gynecomastia. Early detection by endocrine hormone measurements may help preventing gynecomastia. AbstractPosaconazole therapy may lead to increased serum estradiol levels and development of gynecomastia. Early detection by endocrine hormone measurements may help preventing gynecomastia.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
ConclusionJuvenile tGrCT represent a benign entity whereas adult tGCTs have metastatic potential. Tumor size, presence of angiolymphatic invasion or gynecomastia represent risk factors for metastatic disease. The published literature supports the use of testis sparing surgery but there is only limited experience with adjuvant therapies. In the metastatic setting, the reviewed literature suggests that aggressive surgical and systemic treatment might cure patients.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 17 September 2020Source: International Journal of Surgery Case ReportsAuthor(s): Fahmi H. Kakamad, Marwan N. Hassan, Abdulwahid M. Salih, Gasha S. Ahmed, Berwn A. Abdullah, Shvan H. Mohammed
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Source: Aesthetic Plastic Surgery - Category: Cosmetic Surgery Source Type: research
Authors: Trifu SC, Istrate D, Miruna DA Abstract Schizophrenia is considered the most severe and debilitating psychiatric disorder. During the 80's, first reports on abnormalities of the schizophrenic brain which could be objectively observed on MRI, CT scans and other imagistic techniques were published. This showed that schizophrenia is a disorder that goes beyond the functional aspect of the symptomatology. The ties between psychiatry and endocrinology are easily observed, even empirically, by any mental health practitioner, and mirrored by endocrinology specialists. Disorders related to menstruation phase of th...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
AbstractBackgroundGynecomastia is the most common benign disease in males with an increasing prevalence in recent years. It may cause local pain and psychological disorders. The vacuum-assisted breast biopsy system has been reported to be a novel surgical approach for the treatment of gynecomastia. However, there are little detailed reports comparing the curative effect between traditional surgery and vacuum-assisted breast biopsy for gynecomastia. Besides, there was little study which compared the application of two different systems for the treatment of gynecomastia. Our study aimed to investigate the effectiveness of va...
Source: Aesthetic Plastic Surgery - Category: Cosmetic Surgery Source Type: research
Authors: Bargiota A, Oeconomou A, Zachos I, Samarinas M, L Pisters L, Tzortzis V Abstract Androgen deprivation therapy (ADT) is the most effective systemic treatment for prostate cancer and can be succeeded either surgically or pharmaceutically. Both approaches lead to hypogonadism with a large variety of adverse events, including obesity, metabolic syndrome, osteoporosis, sarcopenia, diabetes mellitus, cardiovascular disease, gynecomastia and sexual dysfunction. In addition, undesirable effects on muscle and bone health may have a significant impact not only on the quality of life but also on life expectancy. Curr...
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
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