Syphilis: Overview Video Syphilis: Overview Video
This illustrated video reviews key aspects of the pathology, causes, symptoms, diagnosis, and treatment of syphilis.
The Saskatchewan Health Authority has declared outbreaks of syphilis and HIV in the area of the Battlefords and Lloydminster. Fifteen new cases of HIV were reported in North Battleford between January and May 31.
Journal Name: The International Journal of Biostatistics Issue: Ahead of print
ConclusionDue to the resurgence of oral syphilis cases, clinicians should be aware of the histopathologic features and order the appropriate ancillary studies in suspected cases. Proper histopathologic diagnosis is important to prevent the spread and further re-emergence of this treatable infection and avoid misdiagnosis as nonspecific mucositis.
Syphilis is a sexually transmitted, infectious disease caused by Treponema pallidum. It can manifest clinically in three stages: primary, secondary, and tertiary. While rare, oral syphilis cases are starting to re-emerge. Our objective is to report 2 additional cases of oral syphilis —one case of primary syphilis and 1 case of secondary syphilis—to highlight the need to consider this entity in the histopathologic differential diagnosis of nonspecific mucositis.
Conclusions The connectivity and recurrent diagnoses in this study population suggest potential benefits of targeted interventions to individuals with multiple diagnoses and their partners. Our study highlights the need for enhanced care, increased syphilis testing frequency, and exploring alternative preventative methods among individuals with syphilis rediagnoses to reduce syphilis incidence.
Background Syphilis transmission can be prevented by prompt diagnosis and treatment of primary and secondary infection. We evaluated the performance of a point-of-care rapid syphilis treponemal (RST) test in an emergency department (ED) setting. Methods Between June 2015 and April 2016, men aged 18 to 34 years seeking services in a Detroit ED, and with no history of syphilis, were screened for syphilis with the RST test, rapid plasma reagin (RPR) test, and Treponema pallidum particle agglutination assay (TP-PA). A positive reference standard was both a reactive RPR and a reactive TP-PA. We compared test results in sel...
Conclusions Most patients tested for syphilis, HIV, or chlamydia/gonorrhea in EDs received only 1 test type at that visit, and most visits were nonemergent in nature. Given shared risk factors for multiple STD and high coinfection rates, EDs serving high-risk populations could consider STD cotesting to help reduce transmission of undiagnosed, untreated infections.
Current syphilis tests cannot distinguish between active and past syphilis among patients with serofast rapid plasma reagin (RPR) titers. We investigated whether cytokine profiles might provide insight in the ...
We are reporting the case of a 53-year-old patient with a 10-year history of PD admitted at our Hospital after multiple masses localized in his abdominal wall. His previous records were unremarkable besides past treated syphilis. He had been initially treated with levodopa/benserazide and dopamine agonists, although the latter had to be discontinued due to impulse control disorder that subsequently resolved. Over time, he required continuous subcutaneous apomorphine infusion (CSAI) due to intractable motor fluctuations.
Conditions: Gonorrhea; Chlamydia; Syphilis Intervention: Drug: Doxycycline Hyclate Delayed-Release 200 mg Sponsors: University of California, San Francisco; University of Washington; National Institute of Allergy and Infectious Diseases (NIAID); Mayne Pharma International Pty Ltd; San Francisco Department of Public Health Not yet recruiting