Colchicine Myopathy: A Case Series Including Muscle MRI and ABCB1 Polymorphism Data

We describe two cases of colchicine myopathy which occurred with co-administration of rosuvastatin. From one case, we present the first published data on muscle MRI in this condition. We additionally present an analysis of four genetic polymorphisms in ABCB1 and transcript levels in muscle tissue, and demonstrate the descriptive finding of reduced ABCB1 transcript levels in the colchicine myopathy patients.
Source: Frontiers in Neurology - Category: Neurology Source Type: research