Serum osmolarity and blood viscosity as a potential explanation for the pathophysiology of neuroleptic malignant syndrome.

Conclusions: Our findings indicate that serum osmolarity of NMS group was statistically significantly higher than the controls. In terms of blood viscosity, there was no statistically significant difference between groups. Higher serum osmolarity in NMS patients than controls may be a reflection of a relative hemoconcentration in NMS. KEY POINTS NMS is usually associated with dehydration resulting in fluid-electrolyte imbalance. We compared the NMS episodes with non-NMS hospitalizations (as control group) of the same patients. Serum osmolarity was statistically significantly higher in NMS group than the controls. There was no statistically significant difference between groups in terms of blood viscosity. PMID: 31116616 [PubMed - as supplied by publisher]
Source: International Journal of Psychiatry in Clinical Practice - Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research