The RNA binding protein HuR influences skeletal muscle metabolic flexibility in rodents and humans

Metabolic flexibility can be assessed by changes in respiratory exchange ratio (RER) following feeding. Though metabolic flexibility (difference in RER between fasted and fed state) is often impaired in individuals with obesity or type 2 diabetes, the cellular processes contributing to this impairment are unclear.

Source: Metabolism - Clinical and Experimental - May 22, 2019 Category: Biomedical Science Authors: Randall L. Mynatt, Robert C. Noland, Carrie M. Elks, Bolormaa Vandanmagsar, David S. Bayless, Allison C. Stone, Sujoy Ghosh, Eric Ravussin, Jaycob D. Warfel Source Type: research