Pilot study to test inhaled nitric oxide in cystic fibrosis patients with refractory Mycobacterium abscessus lung infection

Airways of Cystic Fibrosis (CF) patients are Nitric Oxide (NO) deficient which may contribute to impaired lung function and infection clearance. Mycobacterium abscessus (M. abscessus) infection prevalence is increasing in CF patients and is associated with increased morbidity and mortality. Here, we assess the safety and efficacy of intermittent inhaled NO (iNO) as adjuvant therapy in CF patients with refractory M. abscessus lung infection.

Source: Journal of Cystic Fibrosis - May 22, 2019 Category: Respiratory Medicine Authors: Lea Bentur, Michal Gur, Moshe Ashkenazi, Galit Livnat-Levanon, Marko Mizrahi, Asher Tal, Abdi Ghaffari, Yuval Geffen, Micha Aviram, Ori Efrati Tags: Original Article Source Type: research