Allergic reaction upon intravitreal administration of anti–vascular endothelial growth factor agents

Conclusion: Bevacizumab and ranibizumab are derivatives of murine monoclonal antibodies, whereas pegaptanib is an aptamer and aflibercept is a fusion protein of human origin. These chemical origins may allow patients to receive pegaptanib or aflibercept despite having allergy to bevacizumab or ranibizumab.
Source: Retinal Cases and Brief Reports - Category: Opthalmology Tags: Case Report Source Type: research