Organic dust, causing both oxidative stress and Nrf2 activation, is phagocytized by bronchial epithelial cells.

CONCLUSIONS: Bronchial epithelial cells become phagocytic in response to OD exposure, resulting in an increase in endogenous oxidative stress. Nrf2-dependent mechanisms mediate the antioxidant response to OD. PMID: 31116579 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31116579?dopt=Abstract

Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - May 21, 2019 Category: Cytology Authors: McGovern TK, Farahnak S, Chen M, Larsson K, Martin JG, Adner M Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research