A Computer - Aided Drug Designing for Pharmacological inhibition of ALK inhibitors induces apoptosis and differentiation in Non-small cell lung cancer.

CONCLUSION: These investigations denotes that virtual screened compound (PubChem CID- 123449015) is more efficient to be a better prospective candidate for NSCLC treatment having good pharmacological profile than the pre-established compound CEP-37440 (PubChem CID- 71721648) with low rerank score. The identified virtual screened drug have a high potential to act as ALK inhibitors and can show promising results in the research of non-small cell lung cancer (NSCLC). PMID: 31109278 [PubMed - as supplied by publisher]
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research