Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation.

Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation.
Ann Transplant. 2019 May 21;24:291-297
Authors: Lewandowska L, Małyszko J, Joanna Matuszkiewicz-Rowińska J
Abstract
Acute kidney injury (AKI) is a frequent and serious complication of orthotopic liver transplantation (OLT), with a significant impact on mortality, graft survival, and chronic kidney disease. Currently, the diagnosis of AKI is based on changes in serum creatinine, which is a late marker, usually rising when there is already significant damage to the renal parenchyma. During the last 2 decades, various biomarkers have been studied in many clinical situations, mostly after cardiac surgery, in drug-induced AKI, or in sepsis. The present article summarizes the data on those biomarkers that have been evaluated for the prediction of AKI in patients undergoing OLT.
PMID: 31110167 [PubMed - in process]

Source: Annals of Transplantation - May 20, 2019 Category: Transplant Surgery Authors: Lewandowska L, Małyszko J, Joanna Matuszkiewicz-Rowińska J Tags: Ann Transplant Source Type: research