Gastrografin ™ – Induced hyperthyroidism in patients with cystic fibrosis following lung transplantation: A case series
Distal intestinal obstruction syndrome (DIOS) is a common complication in patients with cystic fibrosis (CF) . DIOS occurs in 10 to 40% of all CF-patients. The risk of developing DIOS is considered higher in the early post-transplant period due to dehydration, immobility, intake of opiates and post-operative adynamic gut . Patients suffer from prolonged intestinal passage or even gastric paresis due to polymedication leading to chronic constipation long-term following lung transplant (LTX) .
Authors: Niewiński G, Graczyńska A, Morawiec S, Raszeja-Wyszomirska J, Wójcicki M, Zieniewicz K, Główczyńska R, Grąt M Abstract BACKGROUND Orthotopic liver transplantation (OLT) is the standard of care for end-stage liver disease. The Charlson Comorbidity Index (CCI) was originally created to assess the survival rate of patients with chronic diseases, although it was modified and adopted in OLT recipients as CCI-OLT. MATERIAL AND METHODS In total of 248 consecutive liver transplant recipients with viral cirrhosis in 98 (39.5%) patients were included. CCI-OLT was calculated assigning a weight of 3...
CONCLUSION: Children exhibited important cardiovascular involvement at the time of the renal transplantation. Both of the studied outcomes were independently associated with systolic blood pressure. For this reason, controlling blood pressure seems to be the main therapy to minimize cardiovascular involvement in children with ESRD.
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FDA Drug Safety podcast on azithromycin (Zithromax, Zmax) antibiotic
CONCLUSION: The transition processes in place in CFRCs can be improved by implementing the use of these quality criteria systematically. PMID: 31208888 [PubMed - as supplied by publisher]
Publication date: Available online 18 June 2019Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Ajai Chari, Kejal Parikh, Quanhong Ni, Safiya AbouzaidAbstractBackgroundReal-world data in newly diagnosed multiple myeloma (NDMM) patients are sparse. Using US claims databases, we analyzed treatment patterns, clinical outcomes, and healthcare utilization and costs in patients receiving lenalidomide- and/or bortezomib-containing therapy.MethodsPatient claims were obtained from a large commercial and Medicare database (October 2009 to May 2015). Patients with NDMM who received lenalidomide- and/or bortezomib-containing t...
Publication date: Available online 13 May 2019Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Diego Adrianzen Herrera, Noah Kornblum, Olga Derman, Lizamarie Bachier-Rodriguez, R. Alejandro Sica, Aditi Shastri, Murali Janakiram, Amit Verma, Ira Braunschweig, Ioannis MantzarisAbstractIntroductionIn the United States, autologous hematopoietic cell transplantation (autoHCT) has fallen out of favor over chemotherapy consolidation for non–high-risk acute myeloid leukemia (AML) when allogeneic hematopoietic cell transplantation (alloHCT) is unfeasible, which is common in racial minorities because of donor registry ...
CONCLUSION: Metronidazole, tinidazole, and nitazoxanide are the drugs of choice. Resistance to common antigiardial drugs has increased in recent years. As such, the search for new molecular targets for antigiardial drugs is urgently needed. In general, treatment of asymptomatic carriers is not recommended. Purification of water supply is an important preventive measure. PMID: 31210116 [PubMed - as supplied by publisher]
ConclusionsBlinatumomab is estimated to be cost effective versus inotuzumab in R/R B-cell precursor ALL adults who have received one or no prior salvage therapy from a US payer perspective.
(Reuters Health) - Lack of knowledge among community physicians may be keeping them from raising the possibility of living donor transplants with their patients with liver disease, new survey data suggest.