Considering the Experience of Being One of the Last Mortals

With the development of rejuvenation therapies underway, and accelerating, somewhere ahead lies a dividing line. Some people will be the last to age to death, too comprehensively damaged for the technologies of the time to recover. Everyone else will live indefinitely in youth and health, protected from aging by periodic repair of the underlying cell and tissue damage that causes dysfunction and disease. Where is that dividing line? No one can say in certainty. I look at the children of today, with long lives ahead of them, and find it hard to believe that in a hundred years the problem won't be solved well in time for them to live for as long as they choose. Equally, people in middle age today will certainly benefit greatly from the advent of first generation rejuvenation technologies, such as senolytics, each narrowly focused on one mechanism of aging. Yet I'm skeptical that matters will progress rapidly enough to rescue them. So somewhere between those two points are the people on the very edge; the last mortals. In a sense this isn't terribly profound at all. It is the same story for every as yet uncontrolled medical condition, where the medical research community is working towards effective treatments that will arrive at some uncertain future date. There will be those who are the last to die, just as the therapies that save everyone else are rolling out. It is only the magnitude that is greater in the case of aging - a hundred or a thousand times greater. Does th...
Source: Fight Aging! - Category: Research Authors: Tags: Of Interest Source Type: blogs

Related Links:

AbstractIn this update of the consensus of the Spanish Society of Medical Oncology (Sociedad Espa ñola de Oncología Médica—SEOM) and the Spanish Society of Pathology (Sociedad Española de Anatomía Patológica—SEAP), advances in the analysis of biomarkers in advanced colorectal cancer (CRC) as well as susceptibility markers of hereditary CRC and molecular biomarkers of localized CRC are reviewed. Recently published information on the essential determination ofKRAS,NRAS andBRAF mutations and the convenience of determining the amplification of human epidermal growth factor ...
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 20 September 2020Source: Materials Today: ProceedingsAuthor(s): Mohd Javeed Mehdi, N Srinivasrao, A Sireesha
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
CONCLUSION: The 2010 SPILF-AFSSAPS guiding criteria for Streptococcus pneumoniae CAP are found in very variable proportions and do not, in their current form, make it possible to accurately guide towards a pneumococcal etiology in patients included in the PACSCAN study. PMID: 32950610 [PubMed - as supplied by publisher]
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
Presentation of CF, airway clearance regimens, diabetes in CF, and other highlights from the cystic fibrosis episode of The Cribsiders podcast.Medscape Pediatrics
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pediatrics Commentary Source Type: news
CONCLUSION: Type 4 collagen could predict the presence of significant and advanced fibrosis in NAFLD patients and it would be a useful tool in routine clinical practice. PMID: 32949785 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
This article aims to emphasize the high incidence of injury to associated soft tissue structures and provide general approach considerations to these complex injuries. PMID: 32950216 [PubMed - as supplied by publisher]
Source: The Orthopedic Clinics of North America - Category: Orthopaedics Authors: Tags: Orthop Clin North Am Source Type: research
Publication date: Available online 21 September 2020Source: Biosensors and BioelectronicsAuthor(s): Sujasha Gupta, Subhadip Ghatak, Travis Hery, Savita Khanna, Mohamed El-Masry, Vishnu Baba Sundaresan, Chandan K. Sen
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
 I commend to your attentionthis essay by Hunter (somewhat lengthy in the context of today's short attention spans) and this by Lili Loofbourow (equally lengthy). They make somewhat similar points, with different framing, so pick the one you like. The version in a pistachio shell is that it's pointless to accuse Republicans of hypocrisy, or lying, because they aren't even pretending to actually believe anything they say. It's all bullshit, 100%. That also means it's pointless to try to have a discussion based on facts and logic, because neither of those words means anything to them and their followers. This is tr...
Source: Stayin' Alive - Category: American Health Source Type: blogs
Publication date: Available online 20 September 2020Source: Journal of Theoretical BiologyAuthor(s): Ke Li, James M. McCaw, Pengxing Cao
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
Restrictions for Newport, Bridgend, Merthyr Tydfil and Blaenau Gwent; Whitty calls for ‘break in unnecessary links between households’Whitty: UK could see 200 deaths a day by NovemberVallance says 6,000 new cases a day in UK, doubling every seven daysSummary of key points from Whitty/Vallance Covid briefingFollow Covid rules or see UK deaths return to spring levels, Shapps warnsGlobal coronavirus updates – live2.58pmBSTAnneliese Dodds’ first speech as shadow chancellor to a Labour conference this morning did not take place in the best of circumstances. The conference is online, which means that even...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Politics Coronavirus outbreak Health Chris Whitty Patrick Vallance Labour Science Infectious diseases Scotland Wales Labour conference 2020 Anneliese Dodds Source Type: news
More News: Alzheimer's | Biomedical Science | Child Development | Children | Diabetes | Diarrhoea | Endocrinology | Gastroschisis Repair | Influenza | Pneumonia | Research | Science | Statistics | Tuberculosis | USA Health