Pharmacokinetic Drug Interactions Between Amlodipine, Valsartan, and Rosuvastatin in Healthy Volunteers

ConclusionWhen amlodipine, valsartan, and rosuvastatin were coadministered to healthy volunteers, the pharmacokinetic exposure to valsartan was decreased, but no change in exposure to amlodipine and rosuvastatin occurred. All treatments were well tolerated.Clinical Trial Registrationhttps://cris.nih.go.kr CRIS KCT0001660.FundingKyungDong Pharmaceutical Corp. Ltd., Seoul, Republic of Korea.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research