Chapter 10 - Functionalized magnetic nanoparticles/biopolymer hybrids: Synthesis methods, properties and biomedical applications

Publication date: 2019Source: Methods in Microbiology, Volume 46Author(s): Kakarla Raghava Reddy, Pattubala Adinaraya Reddy, Chandragiri Venkata Reddy, Nagaraj P. Shetti, Bhatula Babu, Koutavarapu Ravindranadh, Muthukonda Venkatakrishnan Shankar, Madhava C. Reddy, Sarvesh Soni, Shivalingegowda NaveenAbstractSuperparamagnetic iron oxide nanoparticles (SPIONs) are the most extensively used functional nanomaterials as antibacterial agents, and for other biomedical applications due to their unique physical, chemical, magnetic and biocompatibility properties. However, due to their small size, particles tend to aggregate by dipole-dipole interactions between magnetic particles, restricting the type of application they can be used for in precision medicine. Therefore, surface modification on SPIONs is required to enhance their properties and biomedical applications. This review summarizes the different synthesis methodologies for preparing magnetic ferrite nanoparticles, and their functionalization with various biopolymers, physico-chemical, magnetic and biological properties of magnetic ferrite particles-functionalized biopolymers, their applications as antibacterial agents, and as magnetic resonance imaging (MRI) contrast agents uses in clinical diagnostic medicine. Various types of substituted ferrite-based nanoparticles were also showed excellent antibacterial properties against different bacteria such as S. aureus, B. subtilis, E. coli, P. aeruginosa, S. marcescens, M. varians,...
Source: Methods in Microbiology - Category: Microbiology Source Type: research