Elevated lipoprotein(a) levels as the cause of cryptogenic stroke in a young Ashkenazi Jewish female.
Elevated lipoprotein(a) levels as the cause of cryptogenic stroke in a young Ashkenazi Jewish female. Can J Ophthalmol. 2019 Jun;54(3):e126-e128 Authors: Lin WV, Vickers A, Prospero Ponce CM, Lee AG PMID: 31109499 [PubMed - in process]
Conclusion: In these novel results, for both RR and absolute risk, treating to SBPs of 120–140 mmHg versus higher targets benefited older patients more than younger patients without an age-related increase in the RR for adverse effects. Nonetheless, because all clinical trials excluded the most frail older patients, clinicians must consider individual patient characteristics such as frailty, autonomy, and cognitive ability when choosing blood pressure targets.
Conclusion: Total volume as well as duration of leisure time cross-country skiing are each continuously, inversely, and independently associated with future risk of hypertension in a white male population.
Conclusion: The overexpression of Kcnq1, Crlf1, Alb and Xirp1 and the inhibition of Galr2, Kcnh1, Ache, Chrm2 and Slc5a7 expression may indicate that a relationship exists between these genes and the cause and/or worsening of hypertension in SHR and SHRSP.
Background: Left atrial strain and strain rate parameters, measured by bidimensional-speckle tracking echocardiography, have been proposed as predictors of atrial fibrillation, stroke, congestive heart failure and cardiovascular death. However, they have not yet been tested in hypertensive disorders of pregnancy. The aim of this study was to assess the prognostic role of global left atrial peak strain (GLAPS) in a population of pregnant women with new-onset hypertension in a medium-term follow-up. Methods: Twenty-seven consecutive women with new-onset hypertension after 20 weeks pregnancy and 23 age-matched, race-matc...
Conclusions: Directly measured community mobility in SS was decreased through 9 weeks following discharge from inpatient rehabilitation. The limited strength of bivariate correlations between clinical measures and number of trips supported the uniqueness of the community mobility construct. Video Abstract available for more insights from the authors (see Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A277).
Conclusions: Stroke leads to significantly larger sensorimotor activation during functional reaching and gripping despite poorer performance. This may indicate an increased sense of effort, decreased efficiency, or increased difficulty after stroke. fNIRS can be used for assessing differences in brain activation during movements in functional positions after stroke. This can be a promising tool for investigating possible neuroplastic changes associated with functional rehabilitation interventions in the stroke population. Video Abstract available for more insights from the authors (see Video Abstract, Supplemental Digit...
Conclusion: Despite recommendations to include stroke patients in PAC selection and goal setting, many former inpatient rehabilitation facility and skilled nursing facility patients report not being involved in either aspect of care. Video Abstract available for more insights from the authors (see Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A273).
Two new grants from the National Institute of Neurological Disorders and Stroke (NINDS) will pave the way for new treatments for neuronal ceroid lipofuscinoses and Charcot Marie Tooth diseases, two groups of rare neurological disorders. The funding, which totals $10 million, will support new research programs led by University of Rochester Medical Center (URMC) neurologists Erika Augustine, M.D., and David Herrmann, M.B.B.Ch., and involve an international team of scientists and clinicians.
Conclusions: Noting the quality concerns of the included trials, this review suggested that CHM appeared to be a promising, well-tolerated add-on therapy to RC for reducing spasticity and improving PSS patients’ daily activities.
Conditions: Traumatic Brain Injury With Prolonged Loss of Consciousness; Stroke; Brain Hypoxia Intervention: Other: Clinical evaluation of consciousness by the Coma Recovery Scale Revised (CRS-R) Sponsors: Centre Hospitalier Universitaire de Nīmes; M2H laboratory, Montpellier University; IMT Mines Alès, Alès, France; University Hospital, Montpellier; Hôpital d’Uzès, Uzès, France; Clinique Fontfroide, Montpellier, France Completed