Substantial Effect of Fenugreek Seeds Aqueous Extract on Serum Estradiol Level in Ovarian Hyperstimulation Syndrome Rat Model.
This study aimed to evaluate the effect of fenugreek seed aqueous (FSA) extract on serum E2 levels in a rat model of OHSS. Methods: A total of 34 female Sprague Dawley rats, aged 18 days old, weighing 40 to 45 g, were randomly divided into negative control, positive control, and treatment groups. A daily dose of 1500 mg/kg per body weight of FSA extract was administrated orally to rats in the treatment group for 13 days. On day eight of the study, OHSS was induced in both positive control and treated groups by subcutaneous injection of pregnant mare's serum gonadotropin 50 IU for four consecutive days, followed by human chorionic gonadotropin 25 IU on the fifth day. The effect of FSA extract was evaluated by measuring the concentration of serum E2 using the enzyme-linked immunosorbent assay. Results: FSA extract reduced serum E2 level significantly in the treated OHSS model (p-value
ConclusionPre-conceptional TSH levels ranging between 0.5-4.5 mU/L does not appear to have a significant effect on IUI outcome of euthyroid women who are negative for thyroid antibodies.
Does it make sense, medically or ethically, when fertility clinics refuse to treat prospective mothers they consider too large?
ConclusionWhile components of a mixture of lipids and lipophilic micronutrients were associated with live birth outcomes following IVF, a larger investigation is necessary to fully evaluate the potential clinical implications.
Authors: Mencaglia L, Cerboneschi M, Ciociola F, Ricci S, Mancioppi I, Ambrosino V, Ferrandi C, Strozzi F, Piffanelli P, Grasselli A Abstract Female fertility plays a decisive role in the reproduction of mammals, with related issues that include oocyte or embryo quality, establishment of pregnancy, and the physiology of the tissues that contribute to reproduction and metabolic disorders associated with reproductive failure. Although reproductive failure may be attributed to various factors in different species, female infertility is largely controlled by a number of molecular signals that can be regulated in a cycl...
AbstractPurpose of ReviewThe classification of morphologically normal sperm has been progressively redefined. Concurrently, our understanding of the significance of sperm morphology in relation to male factor infertility has evolved. In this review, we will discuss the evolution of sperm morphology assessment and factors that contribute to its measurement variability. We will examine the impact of sperm morphology on natural pregnancy, IUI, IVF, and ICSI outcomes.Recent FindingsThere is a lack of consensus on sperm morphology classification, technique, and inter-observer grading variability. Current evidence suggests sperm...
With Father’s Day mere days away, we’re hearing more advertisements for outdoor grills and golf clubs, sailboats and fishing gear. As an infertility counselor, I am glad that Father’s Day is not welcomed with the gush of sentiment that envelops Mother’s Day. Still, a day dedicated to celebrating fatherhood can be difficult for any number of people. Among them are men and women who lost their fathers when they were quite young, and those who have experienced rocky relationships with their dads. There are men who have regrets about their own role as fathers, and older gay men who missed out on fatherh...
About 13 out of every 100 couples cannot get pregnant. It's a stressful and emotional time, and it's often considered a female issue. The CDC says both men and women contribute to infertility in about 35 percent of couples. The man is the only factor in about eight percent of cases. Dr. Tara Narula joins "CBS This Morning" to discuss some of the causes of male infertility and why it's so difficult for men to talk about the issue.
Conditions: Infertility; Aneuploidy Intervention: Procedure: Laser Acupuncture Sponsor: University of British Columbia Not yet recruiting
AbstractObjectiveTo determine whether younger oocyte donor age is associated with better outcomes after in vitro fertilization (IVF) compared with older oocyte donor age.DesignA retrospective cohort study.SettingLarge academically affiliated infertility treatment center.PatientsWe included all women ≥ 18 years who started their first fresh cycle using donor oocytes at our center from January 2002 through October 2017; only the first oocyte recipient cycle was analyzed.InterventionLog-binomial regression was used to compare the incidence of clinical pregnancy and live birth among the following donor age groups:
Publication date: Available online 7 June 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Boughizane Sassi, Bannour Badra, Rjiba Ghada, Bannour Imen, El Abed Meriem, Khairi Hedi