Glomerular disease patients have higher odds not to reach quality targets in chronic dialysis compared with CAKUT patients: analyses from a nationwide German paediatric dialysis registry

AbstractBackgroundPaediatric dialysis patients still suffer from high morbidity rates. To improve this, quality assurance programs like the German QiNKid (Quality in Nephrology for Children)-Registry have been developed. In our study, the significance of underlying renal disease on a range of clinical and laboratory parameters impacting morbidity and mortality was analysed. Our aim was to evaluate whether or not disease-specific dialysis strategies should be considered in planning dialysis for a patient.MethodsInclusion criteria were defined as follows: (1) CAKUT (congenital anomalies of the kidney and urinary tract) or glomerular disease patient, (2)
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research

Related Links:

CONCLUSION: Eculizumab improved intravascular hemolysis and reversed clinical manifestations of INCPH in a patient with paroxysmal nocturnal hemoglobinuria. PMID: 31183008 [PubMed]
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
CONCLUSION: We report liver pathology findings of CDA1 with a novel genetic mutation for the first time in a newborn. PMID: 31183007 [PubMed]
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
Abstract BACKGROUND: Mortality after myocardial infarction is higher in women than in men. Data on the association between sex and mortality are conflicting and inconclusive. We evaluated whether there is a sex difference in survival and if sex is associated with the outcome in patients with ST-elevation myocardial infarction (STEMI). METHODS: We analyzed 3671 STEMI patients. Long-term and 30-day mortality in men and women were compared. RESULTS: Unadjusted mortality at day 30 was higher in women [221 (8.7%) men died compared to 147 (13.1%) women; p 
Source: European Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Eur J Intern Med Source Type: research
Abstract The case of a 61-year-old male with a recent total gastrectomy for a hemorrhagic gastric tumor is presented, with the important co-morbidities of type II diabetes mellitus requiring insulin, chronic hepatitis C with liver dysfunction, stage II essential hypertension, chronic stage III renal disease peripheral type II aorto-iliac disease with stage II ischemia of both legs, and chronic anemia. About one month following the gastrectomy, the patient presented with fever and acute inflammatory syndrome. Severe aortic insufficiency, aortic valvular vegetations, and positive blood cultures with Staphylococcus s...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
Purpose of review Recent research has revealed that regulation of the bone-secreted hormone fibroblast growth factor 23 (FGF23) is not limited to classical mineral factors. Specifically, bidirectional relationships have been described between FGF23 production and anemia, iron status, and inflammation. Here, we will review the latest published articles on the crosstalk between FGF23 and the aforementioned nonclassical factors. Recent findings It has been recently reported that erythropoietin, iron deficiency, and inflammation increase FGF23 production and metabolism. Moreover, FGF23 promotes anemia and regulates inflam...
Source: Current Opinion in Nephrology and Hypertension - Category: Urology & Nephrology Tags: MINERAL METABOLISM: Edited by Aline Martin and Tamara Isakova Source Type: research
Publication date: June 2019Source: Neurophysiologie Clinique, Volume 49, Issue 3Author(s): Z. Affes, F. Lionnet, J.P. Lefaucheur, J.P. HaymannBackgroundImpairment of autonomic nervous system seems underestimated in SCA.ObjectivesTo assess the prevalence of sudomotor dysfunction in SCA patients, and to identify relevant associated clinical/biological phenotypes.MethodsA total of 90 adult homozygous SCA patients–exclusively sub-Saharan-African-native–referred to our centre for a routine-follow-up were included. Clinical and biological data were collected as well as electrochemical skin conduction (ESC) measuremen...
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
ConclusionsMales and females with HF showed different characteristics across the EF spectrum. Males reported a lower crude risk of mortality/morbidity in HFpEF and HFmrEF but higher risk of HFrEF, although after adjustments, prognosis was better in females regardless of EF. The observed sex-related differences highlight the need for an adequate representation of females in HF randomized controlled trials to improve generalizability.Central Illustration
Source: JACC: Heart Failure - Category: Cardiology Source Type: research
ConclusionsAmbulatory blood pressure monitoring is superior to casual office BP obtained at time of dialysis in delineating cardiovascular morbidity in adolescent and young adult HD patients. CBP is easily performed and correlates with LVMI and PWV in adolescent and young adult HD patients; however, large-scale normative data is needed.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
Semin intervent Radiol 2019; 36: 072-075 DOI: 10.1055/s-0039-1688418Transjugular intrahepatic portosystemic shunt (TIPS) creation is a minimally invasive technique aimed at managing the complications of portal hypertension. Initially performed in the setting of variceal bleeding, the role of TIPS has expanded to treatment of medically refractory ascites, portal hypertensive gastropathy, hepatic hydrothorax, Budd-Chiari syndrome, portal vein thrombus, and hepatorenal syndrome. Potential complications from TIPS are well documented, and include hepatic encephalopathy, hepatic failure, and TIPS dysfunction. Hemolytic anemia is...
Source: Seminars in Interventional Radiology - Category: Radiology Authors: Tags: Review Article Source Type: research
ConclusionsMaternal anemia after MS may lead to low neonatal birth weight, which could be attributed to the large-scale reduction in maternal micronutrient levels.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
More News: Anemia | Calcium | Children | Dialysis | Germany Health | Hemodialysis | Hormones | Hypertension | Laboratory Medicine | Pediatrics | Peritoneal Dialysis | Study | Urology & Nephrology