Ultrasound-guided injections in musculo-skeletal system - An overview

Publication date: Available online 22 May 2019Source: Journal of Clinical Orthopaedics and TraumaAuthor(s): Amit Kumar Sahu, Prasandeep Rath, Bharat AggarwalAbstractUltrasound guided musculoskeletal injection has a wide range of indication in joint, muscle, tendon, nerve, ganglion and bursa pathologies. These are less invasive procedures and provide desirable results in short duration. Local anesthetics and corticosteroids are the most commonly injected pharmaceuticals. Platelet rich plasma and autologus blood injections have gained popularity in recent past and provide acceptable results. In this article we aim to review the general consideration, indications, technique and pharmaceuticals used in common therapeutic musculoskeletal injections.
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research

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Publication date: Available online 23 June 2019Source: Progress in Retinal and Eye ResearchAuthor(s): Muneeb A. Faiq, Gadi Wollstein, Joel S. Schuman, Kevin C. ChanAbstractThe cholinergic system has a crucial role to play in visual function. Although cholinergic drugs have been a focus of attention as glaucoma medications for reducing eye pressure, little is known about the potential modality for neuronal survival and/or enhancement in visual impairments. Citicoline, a naturally occurring compound and FDA approved dietary supplement, is a nootropic agent that is recently demonstrated to be effective in ameliorating ischemi...
Source: Progress in Retinal and Eye Research - Category: Opthalmology Source Type: research
ConclusionAs a composite scaffold, an NT-3 sustained-release system cross-linked with an acellular spinal cord scaffold has potential applications for tissue engineering.Graphical abstract
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Condition:   Thoracic; Sympathetic Ganglion, Injury Intervention:   Other: thoracic sympathetic ganglion block Sponsor:   Keimyung University Dongsan Medical Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractGentamicin, one of the most widely used aminoglycoside antibiotics, is known to have toxic effects on the inner ear. Taken up by cochlear hair cells and spiral ganglion neurons (SGNs), gentamicin induces the accumulation of reactive oxygen species (ROS) and initiates apoptosis or programmed cell death, resulting in a permanent and irreversible hearing loss. Since the survival of SGNs is specially required for cochlear implant, new procedures that prevent SGN cell loss are crucial to the success of cochlear implantation. ROS modulates the activity of the mammalian target of rapamycin (mTOR) signaling pathway, which ...
Source: JARO - Journal of the Association for Research in Otolaryngology - Category: ENT & OMF Source Type: research
Publication date: Available online 21 June 2019Source: Medicina Intensiva (English Edition)Author(s): J. Sánchez Arguiano, M.A. Hernández-Hernández, R.A. Jáuregui Solórzano, S. Maldonado-Vega, A. González Mandly, J. Burón Mediavilla
Source: Medicina Intensiva - Category: Intensive Care Source Type: research
Authors: Esquiva G, Hannibal J Abstract Melanopsin-expressing retinal ganglion cells (mRGCs) constitute a system in the mammalian retina used for irradiance detection, regulating non-image forming functions, such as photoentrainment of circadian rhythms, control of the pupillary light reflex, masking response, light-regulated melatonin secretion, and modulation of the sleep/wake cycle. There are five subtypes of mRGCs differentiated by morphology and function. Recent years of research on mRGCs have identified a broad number of neurodegenerative diseases in the eye and the brain with altered physiologic light respon...
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
In conclusion, EA exerts antihyperalgesic effect in a rat model of conscious recurrent migraine, possibly via modulation of the vasoactive neurotransmitters. Furthermore, targeting multiple acupuncture points is more effective than targeting a single point in reducing hyperalgesia. PMID: 31217804 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Publication date: Available online 18 June 2019Source: NeuronAuthor(s): Colleen E. Rhoades, Nishal P. Shah, Michael B. Manookin, Nora Brackbill, Alexandra Kling, Georges Goetz, Alexander Sher, Alan M. Litke, E.J. ChichilniskySummaryThe functions of the diverse retinal ganglion cell types in primates and the parallel visual pathways they initiate remain poorly understood. Here, unusual physiological and computational properties of the ON and OFF smooth monostratified ganglion cells are explored. Large-scale multi-electrode recordings from 48 macaque retinas revealed that these cells exhibit irregular receptive field structu...
Source: Neuron - Category: Neuroscience Source Type: research
Abstract BACKGROUND: Acupuncture has been used to treat myofascial pain syndrome (MPS) for 2000 years in China, but its mechanisms are still not entirely clear. In the present study, we explored the effects of transcutaneous electrical acupuncture point stimulation (TEAS) at an Ashi acupuncture point on expression of phosphorylated c-Jun N-terminal kinase (p-JNK) in the dorsal root ganglion (DRG) using a rat model of MPS. METHODS: 32 rats were divided into four groups: normal, MPS, MPS+TEAS and MPS+sham- TEAS. MPS was produced by a blunt strike to the left vastus medialis combined with eccentric...
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - Category: Complementary Medicine Authors: Tags: Acupunct Med Source Type: research
CONCLUSIONS: To our knowledge, this is the first ever case report describing a thinning of ganglion cell complex in a patient with incipient nonarteritic anterior ischemic optic neuropathy. This suggests that contrary to current belief, incipient nonarteritic anterior ischemic optic neuropathy can result in subclinical structural changes to the affected eye. PMID: 31218884 [PubMed - as supplied by publisher]
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Eur J Ophthalmol Source Type: research
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