Relation of Body Mass Index Categories with Risk of Sudden Cardiac Death.
Relation of Body Mass Index Categories with Risk of Sudden Cardiac Death. Int Heart J. 2019 May 17;: Authors: Chen H, Deng Y, Li S Abstract The aim of this study was to evaluate the association of the body mass index (BMI) categories with the risk of sudden cardiac death (SCD) in a systematic review and meta-analysis.We systematically searched the PubMed, Embase, and Cochrane Library databases up to February 2018 for all studies reporting an association between BMI and risk of SCD. Relative risks (RRs) and 95% confidence intervals (CIs) were extracted and pooled using a random effects model.A total of 10 studies involving 1,381,445 participants were included in the meta-analysis. Overall, compared with the risk level in normal-weight controls, being underweight was not associated with increased risk of SCD (RR = 1.20, 95% CI, 0.95-1.51; P = 0.13). In contrast, both being overweight (RR = 1.21, 95% CI, 1.08-1.35; P = 0.0008) and obesity (RR = 1.52, 95% CI, 1.31-1.77; P
Predicting lifespan isn’t an exact science. U.S. life expectancy is currently estimated at 78.6 years, but that one number doesn’t tell the whole story. Genes, gender, lifestyle and luck all play an important part, but it’s impossible to know exactly how much and in what proportion each ingredient influences a person’s longevity. The single best predictor, though, might not be one of these factors at all. A growing body of evidence suggests it may be a person’s zip code that holds the most information about how long they’ll live. Researchers from the New York University School of Medicin...
TYPE 2 diabetes is a common condition caused by the body ’s inability to produce enough insulin to regulate blood sugar levels. It is strongly linked to being overweight and poor dietary decisions. Sticking to a low-carb meal plan can help to mitigate the risks associated with the life-long condition.
Authors: Brignardello-Petersen R PMID: 31200895 [PubMed - as supplied by publisher]
Neuropsychopharmacology, Published online: 17 June 2019; doi:10.1038/s41386-019-0437-1Early-life high-fat diet-induced obesity programs hippocampal development and cognitive functions via regulation of gut commensal Akkermansia muciniphila
ConclusionsSNPs rs10189761 and rs737337 were identified, for the first time, as independent predictors of major clinical outcomes in patients with HF. The data suggests an additive predictive value of these SNPs for a HF prognosis. In particular for obese patients, SNPs rs10423928, rs1800437, rs737337 and rs9351814 were related with a bad prognosis. Combined scores weighting the risk of each genomic variant could effect interesting new tools to stratify the prognostic risk of HF patients.
International Journal of Obesity, Published online: 17 June 2019; doi:10.1038/s41366-019-0402-4Pentraxin 3 deficiency exacerbates lipopolysaccharide-induced inflammation in adipose tissue
International Journal of Obesity, Published online: 17 June 2019; doi:10.1038/s41366-019-0392-2No impact of hunger on male perception of female physical attractiveness in relation to adiposity: a randomized controlled trial
International Journal of Obesity, Published online: 17 June 2019; doi:10.1038/s41366-019-0396-yAssociation between Transcription Factor AP-2B genotype, obesity, insulin resistance and dietary intake in a longitudinal birth cohort study
International Journal of Obesity, Published online: 17 June 2019; doi:10.1038/s41366-019-0394-0Change, predictors and correlates of weight- and health-related quality of life in adolescents 2-years following bariatric surgery
ConclusionWe present a comprehensive mRNA expression profile of chromogranin A positive enteroendocrine cells following RYGB in rats. The data provides a region-specific characterization of all regulated preprohormone encoding genes in the rat GI tract including 16 not hitherto known. The comprehensive catalogue of preprohormone expression changes may support our understanding of hormone mediated effects of RYGB on diabetes remission and body weight reduction.Graphical abstract