Girl, nine, with severe eczema saves her skin with chemotherapy drug

Honor Stanmore was kept awake all night 'scratching until she bled' due to the chronic skin condition. But her skin has cleared up after taking part in a NHS research trial at Oxford's Churchill Hospital.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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This study aims to investigate the influence of BAHS and associated skin reactions around the implant. A total of 45 patients were prospectively followed from implantation up to at least 1 year. Swabs were obtained at baseline, 12 weeks follow-up and during cases of inflammation (Holgers score ≥2). The microbiota was assessed using IS-proTM, a bacterial profiling method based on the interspace region between the 16S–23S rRNA genes. Detection of operational taxonomic units, the Shannon Diversity Index, sample similarity analyses and Partial Least Squares Discriminant Analysis (PLS-DA) were employed. Staphylococcus ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
AbstractTargeted therapies and immunotherapies are associated with a wide range of dermatologic adverse events (dAEs) resulting from common signaling pathways involved in malignant behavior and normal homeostatic functions of the epidermis and dermis. Dermatologic toxicities include damage to the skin, oral mucosa, hair, and nails. Acneiform rash is the most common dAE, observed in 25 –85% of patients treated by epidermal growth factor receptor and mitogen-activated protein kinase kinase inhibitors. BRAF inhibitors mostly induce secondary skin tumors, squamous cell carcinoma and keratoacanthomas, changes in pre-exist...
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
(Natural News) After battling with eczema and psoriasis for the last two decades, Hanna Sillitoe has finally found a cure. The 38-year-old from Manchester says that switching to an anti-inflammatory diet has changed her life. At one point, Sillitoe’s skin conditions were so difficult to treat, doctors suggested she try chemotherapy. Instead, Sillitoe started doing...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Harry and his father at Dana/Farber-Boston Children’s In their Brookline home-away-from-home, 2-year-old Duy Anh “Harry” Le plays with blocks and pop-up toys on the floor with his mother, Thao Nguyen. He is lively and happy, and his skin is clear. He looks almost nothing like the sickly baby covered in eczema who arrived in Boston from his native Vietnam in November of 2016 to participate in a gene therapy clinical trial for Wiskott-Aldrich syndrome. Children with the potentially life-threatening, inherited immune system deficiency have difficulty producing platelets, the blood component that fosters clot...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Diseases & Conditions Our Patients’ Stories Dana-Farber/Boston Children's Cancer and Blood Disorders Center Dr. Sung-Yun Pai gene therapy Wiskott-Aldrich syndrome Source Type: news
In conclusion, this patient combined an isotopic response and ESK.Case Rep Dermatol 2017;9:35 –39
Source: Case Reports in Dermatology - Category: Dermatology Source Type: research
A 68-year-old female cachectic patient with pancreatic ductal adenocarcinoma (after pancreatectomy 44 months ago, followed by chemotherapy with gemcitabine for 6 months), was admitted to our department of for further diagnosis of skin lesions. The skin lesions clinically appeared as extensive sclerosis distributed on the feet, especially on their dorsal aspects, legs, knees and inner thigh area. They had progressed for the following 12 months. Keratinization and eczema craqel é like were observed on the calves.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Sign-up here for a set of week-by-week newsletters so you can follow your baby’s development from now until the beautiful moment of birth. Get Dr. Greene's Pregnancy Newsletter Sign up for Dr. Greene's FREE week-by-week newsletter, timed to your pregnancy to keep you up to date on every stage of your baby's development. Success! Now check your email to confirm your subscription. There was an error submitting your subscription. Please try again. First Name Your baby's due date? ...
Source: Conversations with Dr Greene - Category: Child Development Authors: Tags: Uncategorized Source Type: blogs
AbstractFive patients with refractory/relapsed classical Hodgkin lymphoma (cHL), four having failed multiple lines of chemotherapy and brentuximab vedotin, were treated with low-dose pembrolizumab (median dose 100  mg, range: 100–200 mg, every 3 weeks). Complete response (CR) was achieved in four patients (80%), after a median cumulative dose of merely 495 (300–800) milligrams. Three CR patients have continued to receive pembrolizumab for a median of 16 (14–25) cycles, remaining in CR for a median of 18 (9–18) months. One CR patient underwent autologous hematopoietic stem cell transpl...
Source: Annals of Hematology - Category: Hematology Source Type: research
Ethan Cavanagh, seven, from Liverpool, takes 5.5ml of chemotherapy drugs every morning. It is hope this will stop his immune system attacking itself and help manage his severe eczema.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell li...
Source: World Allergy Organization Journal - Category: Allergy & Immunology Source Type: research
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