Effectiveness of behavioural interventions to reduce urinary tract infections and Escherichia coli bacteraemia for older adults across all care settings: a systematic review

ConclusionThe heterogeneity of studies means that one effective intervention cannot be recommended. We suggest that feedback should be considered because it facilitated reductions in UTI when used alone or in multi-faceted interventions including education, audit or catheter removal protocols. Multi-faceted education is likely to be effective. Catheter removal protocols, increased staffing, and patient education require further evaluation.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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CONCLUSION: The recognition of E. coli captured by phagosomes or partially damaged by lysosomal attack within the cell was recorded for the first time. Furthermore, SEM observation was performed on human tissue. PMID: 31298302 [PubMed - as supplied by publisher]
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
Publication date: November 2019Source: Materials Science and Engineering: C, Volume 104Author(s): Sinem Diken Gür, Monireh Bakhshpour, Adil DenizliAbstractThe aim of the present study was developing a surface plasmon resonance (SPR) nanosensor to detect Escherichia coli (E. coli) for the diagnosis of urinary tract infections by using surface imprinted Au nanoparticles (AuNPs) as a recognition element. In order to realize imprinting, Cu(II) ions were used to provide interaction between E. coli cell wall and amine functionalized AuNPs forming cavities on the surface of nanosensor. E. coli surface imprinted AuNPs nanosen...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 18 May 2019Source: Microbial PathogenesisAuthor(s): Alireza Vasiee, Seyed Ali Mortazavi, Mojtaba Sankian, Farideh Tabatabaee Yazdi, Mahmoud Mahmoudi, Fakhri ShahidiAbstractDeath from infectious diseases has caused concerns about increases in the resistance of pathogens, impelling researchers to create novel therapeutic solutions. The management of intestinal tract problems has been the advance use of probiotics in medicine. The aim of this study was evaluate the physicochemical cell surface and adhesion properties of recombinant Lacotococcus lactis NZ1330 containing Ama r 2 gene, followed...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
This study also found that Proteus DNA, a genus with many uropathogenic species (Drzewiecka, 2016), was more prevalent in women with OAB compared to asymptomatic controls (Curtiss et al., 2017). IC A recent study by Abernethy et al. suggested that the microbiome may play a role in IC (Abernethy et al., 2017). In this study, 16S rRNA analysis determined the microbiome of catheterized urine from women (n = 40) with IC was not dominated by a single genus and was less likely to contain Lactobacillus compared to asymptomatic women. Abernethy et al. also showed that L. acidophilus was associated with less severe scores on the ...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Abstract Diabetes mellitus (DM) is a common disease in Oman as in rest of Gulf Cooperation Council where metabolic syndrome is of high prevalence. DM is a foremost risk factor for urinary tract infections (UTIs). It is also linked to more complicated infections such as emphysematous pyelonephritis (EPN), emphysematous pyelitis (EP), renal/perirenal abscess, emphysematous cystitis, xanthogranulomatous pyelonephritis, and renal papillary necrosis. The diagnosis of these cases is frequently delayed because the clinical manifestations are generic and not different from the typical triad of upper UTI, which include fev...
Source: Saudi Journal of Kidney Diseases and Transplantation - Category: Urology & Nephrology Authors: Tags: Saudi J Kidney Dis Transpl Source Type: research
In conclusion, we unraveled a mechanism of immune evasion of Kpn KPC ST258, which may contribute to design more effective strategies for the treatment of these multi-resistant bacterial infections. Introduction Klebsiella pneumoniae (Kpn) is a Gram-negative pathogen causing a wide range of infections from urinary tract infections to pneumonia. Kpn is a member of the so-called ESKAPE group of microorganisms, a term that emphasizes the fact that they effectively “escape” the effects of antibacterial drugs (1). Antimicrobial resistance is a significant problem for the treatment of infectious diseases caused ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
In this study, we sought to establish a new, carefully optimized method to extract and purify non-denatured, native FliC from the reference UPEC strain CFT073 to be suitable for immune assays. To achieve purification of FliC to homogeneity, we used a mutant CFT073 strain containing deletions in four major chaperone-usher fimbriae operons (type 1, F1C and two P fimbrial gene clusters; CFT073Δ4). A sequential flagella extraction method based on mechanical shearing, ultracentrifugation, size exclusion chromatography, protein concentration and endotoxin removal was applied to CFT073Δ4. Protein purity and integrity ...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Publication date: Available online 13 April 2019Source: Materials Science and Engineering: CAuthor(s): Harish Chandra, Deepak Patel, Pragati Kumari, J.S. Jangwan, Saurabh YadavAbstractThe field of nanoscience or nanotechnology is gaining popularity day by day and it is now well established field of interdisciplinary sciences. Nanoparticles are synthesized by various methods but suffer from few limitations such as toxicity. To overcome the limitations of various synthesis methods, the focus has shifted to new radius which involves biological organisms such as plants i.e. green synthesis. This phyto-mediated approach using v...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
In this study they also showed PTX3 localized in NETs formed after neutrophil activation (5). Proteomics analysis revealed that PTX3 forms complexes with two anti-microbial proteins [azurocidin (AZU1) and myeloperoxidase (MPO)] associated to NETs (30). More recently, PTX3 localization in NETs has been confirmed, and the colocalization with AZU1 and MPO has been defined more accurately (31). Further investigation will be needed to understand the involvement of PTX3 interaction with AZU1 and MPO in their antibacterial role during NET formation. Regulation of Complement Activation PTX3 interaction with microorganisms is not...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
In this study, 12 O-antigen gene clusters of P. shigelloides, O2H1a1c (G5877), O10H41 (G5892), O12H35 (G5890), O23H1a1c (G5263), O25H3 (G5879), O26H1a1c (G5889), O32H37 (G5880), O33H38 (G5881), O34H34 (G5882), O66H3 (G5270), O75H34 (G5885), and O76H39 (G5886), were sequenced and analyzed. The genes that control O-antigen synthesis are present as chromosomal gene clusters that maps between rep and aqpZ, and most of the synthesis and translocation of OPS (O-specific polysaccharide) belongs to Wzx/Wzy pathway with the exception of O12, O25, and O66, which use the ATP-binding cassette (ABC) transporter pathway. Phylogenetic an...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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