Glucose-6-phosphate dehydrogenase deficiency reduces susceptibility to cancer of endodermal origin.
CONCLUSIONS: Our results suggest a reduced susceptibility to develop cancers, mostly of endodermal origin (stomach, colon and liver), but not of ectodermal/mesodermal origin, in carriers of G6PD deficiency. The effects of G6PD deficiency on carcinogenesis need further studies to better understand how cancer cells originating from different germ layers use pentose phosphate pathway to proliferate.
PMID: 31109224 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Pes GM, Errigo A, Soro S, Longo NP, Dore MP Tags: Acta Oncol Source Type: research
More News: Breast Carcinoma | Cancer | Cancer & Oncology | Carcinoma | Colon Cancer | Colorectal Cancer | Diabetes | Endocrinology | G6PD | Gastric (Stomach) Cancer | Gastroenterology | Hepatocellular Carcinoma | Italy Health | Liver | Liver Cancer | Smokers | Study | Teaching | Teaching Hospitals | Universities & Medical Training | Urology & Nephrology