Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis.

Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis. Ren Fail. 2019 Nov;41(1):408-418 Authors: Chen G, Gao L, Li X Abstract BACKGROUND: Whether exercise can improve cardiovascular health in kidney transplant recipients (KTRs) is unclear. Therefore, we performed a systematic review of the effects of exercise on cardiovascular risk factors in this population setting. METHODS: Randomized control trials (RCTs) evaluating the impact of exercise on major clinical outcomes in KTRs were identified by searches in Cochrane CENTRAL, PubMed, EMBASE, OVID and CBM updated to December 2018. The main outcomes of interest were blood pressure, lipid profile, blood glucose level, arterial stiffness, kidney function, body weight, body mass index, exercise tolerance (VO2 peak) and quality of life (QOL). RESULTS: After screening 445 studies in the database, we included 12 RCTs in the review and 11 RCTs for further qualitative analysis. The results indicate a significant improvement in small arterial stiffness [mean difference (MD): -1.14, 95% confidence interval (CI): -2.19-0.08, p = .03], VO2 peak (MD: 2.25, 95% CI: 0.54-3.69, p = .01), and QOL (MD: 12.87, 95% CI: 6.80-18.94, p
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research

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We report here a huge ADPKD case of kidney transplantation concomitant with simple nephrectomy through thoracoabdominal approach that allows surgeons to manipulate the renal vessels, the adrenal grand, the trigonal ligament, and the lower pole of the kidney under the wide operative field. Because of the direct recognition of the surgical anatomy, it might be safe and feasible for simple nephrectomy in huge ADPKD patients undergoing concomitant kidney transplantation despite of the wide skin incision required by this approach.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
ConclusionVascular surgery in TA cases becomes an option when the patient does not improve clinically after administration of medical treatment. Although endovascular management has fewer complications, the rate of restenosis is higher. Patients at risk of restenosis and who have increased perioperative vascular risk can benefit from open surgical procedures. Surgical management should be tailored to the patient’s needs.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionNo conclusion can be drawn on the contribution of somatostatin analogs and immunosuppressant in the occurrence of severe cholecystitis. Prophylactic cholecystectomy is not indicated in patients with this medication.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We describe a technique for osteochondral allograft transplantation to the patella for an isolated patellar chondral lesion (unipolar).
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
In this study, we investigated the genetic contribution to renal disease in Tiwi Islanders by conducting a GWAS, in which associations were tested between SNP genetic variants and single measure ACR levels. A number of nominally significantly associated SNPs were identified. These SNPs did not reach genome wide significance, probably due to the small sample size. The top eight SNPs were re-tested for association in a separately collected cohort from the same population. Four of these SNPs were significantly associated with ACR in the replication sample (p
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Morbid obesity has been defined by the WHO as a global epidemic. The incidence of obesity among the renal transplant population is on the rise, with obesity-mediated diseases, such as type 2 diabetes mellitus (T2D), dyslipidemia and hypertension, being considered the leading causes of end-stage renal disease. Moreover, gaining weight after transplantation is a very common occurrence in most kidney transplant patients [1], and obesity is an independent risk factor for chronic renal failure [2].
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
Conclusion: A high rate of patients not adherent to the immunosuppressive treatment was identified (41.4%). There was no significant correlation between creatinine level and receptor age at time of KTP, time after KTP, immunosuppressive separation time and total score and scores of individual BAASIS® items. T his study showed that black, male recipients without a family support network, obese and autonomous are more likely not to adhere to immunosuppressive therapy. The evaluation of renal transplant recipient adhesion should be considered during all phases of the nursing process actions that make up the therapeutic pl...
Source: Acta Paulista de Enfermagem - Category: Nursing Source Type: research
ConclusionIn this specific group of high-risk patients, SG showed encouraging results in terms of weight loss and resolution/improvement of comorbidities, renal function, and quality of life.
Source: Obesity Surgery - Category: Surgery Source Type: research
ConclusionsAccording to the results of this small sample series, LSG seems to be an effective and safe procedure in DDRF patients with concomitant obesity and can increase access to transplantation.
Source: Obesity Surgery - Category: Surgery Source Type: research
Conclusions: In this longitudinal sample of older men, the findings supported the hypothesis that long-term PM2.5 exposure negatively affects renal function and increases renal function decline. Citation: Mehta AJ, Zanobetti A, Bind MC, Kloog I, Koutrakis P, Sparrow D, Vokonas PS, Schwartz JD. 2016. Long-term exposure to ambient fine particulate matter and renal function in older men: the VA Normative Aging Study. Environ Health Perspect 124:1353–1360; http://dx.doi.org/10.1289/ehp.1510269 Address correspondence to A.J. Mehta, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Landmar...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Article September 2016 Source Type: research
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