Randomized Double-blind Comparison of Bolus Phenylephrine or Ephedrine for Treatment of Hypotension in Women With Preeclampsia Undergoing Caesarean Section
(Anaesthesia. 2018;73:839–846) Preeclampsia is a common complication of pregnancy. In the past, anesthesiologists had sometimes avoided the use of spinal anesthesia in parturients with preeclampsis due to concerns about spinal-induced hypotension leading to inadequate uteroplacental perfusion. However, more recent studies have shown spinal anesthesia to be a safe technique in preeclamptic women as the hypotension associated with it is less severe than that experienced by normotensive parturients and is easily treated. However, effective treatment of postspinal hypotension remains an important component of anesthetic management. While phenylephrine has become the vasopressor of choice for treatment of hypotension in healthy women undergoing cesarean section due to the lower risk of fetal acidosis, the preferred vasopressor for preeclamptic women remains unclear. This randomized, double blind study was performed to compare the effects of phenylephrine versus ephedrine for the treatment of spinal-induced hypotension in preeclamptic women undergoing cesarean section.
This study aimed to explore the association between serum syndecan-1 and glypican-3 levels and the adverse perinatal outcome as well as the responses to the treatment of ursodeoxycholic acid (UDCA).MethodsThis prospective, case control study included 88 pregnant women (44 women with ICP and 44 healthy controls). The primary end points were the perinatal outcome and the response to UDCA therapy. A logistic regression model was used to identify the independent risk factors of adverse pregnancy outcomes and reduced response to UDCA therapy.ResultsWomen with ICP had significantly higher serum syndecan-1 (1.27 ± 0.36 ng/...
Antiphospholipid antibody syndrome (APS) is an autoimmune disease characterized by thromboembolic events or pregnancy-related complications caused by antiphospholipid antibodies. The following case reports a patient diagnosed with APS, osteoporosis, and atherosclerosis. The medication for treatment and control of the diseases were warfarin, low-molecular-weight heparin, aspirin, and alendronate. Clinical and radiographic examination revealed an intraoral fistula, with spontaneous purulent drainage in a 2-month previous tooth extraction area and signs of bone sequestrum both compatible with medication-related osteonecrosis of the jaw (MRONJ).
An 18-year-old female patient who had a 1-year-old daughter came to us presenting a 2-week lesion that has begun as a "bubble." Examination showed an asymptomatic smooth white lesion without ulcerations in lower lip mucosa and minor lesions on tongue. She was a healthy patient, had no previous lesion, and had a normal pregnancy demonstrated by her health card. Blood count had normal parameters. She reports not to have a sexually active life, and denies habits of smoking and alcoholism. After examination, autoimmune lesions were suspected.
This study reports the case of mandibular intraosseous lesion in pregnant women, addressing tomographic dose, type of anesthetic procedure, moment of intervention, and outcome of treatment. The patient is 44 years old with complaint of lack of sensitivity in the mental region. She was on the third gestational month, and had done cone beam tomography. Clinical examination revealed a slight increase in mandibular volume, absence of decayed teeth, or periodontal pocket in the involved teeth.
We present the case of a 49-year-old female patient who presented with a gingival nodule perceived during pregnancy that persisted about 18 years. Histologic sections stained with hematoxylin and eosin (HE) revealed fragments of mucosa with parakeratinized stratified squamous epithelium underlined by highly cellular connective tissue with plump fibroblast arranged in interlacing fascicles was seen.
[Citizen] It is very uncommon for people that I know, to visit the doctor when they are not sick. For most adults that I know, they will go to hospital when they are not sick only when they need a clean bill of health certificate maybe needed to join a college or a job with a new institution. Or for an HIV test, when one is in a serious relationship and/or wants to get married, or when one is pregnant.
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Rui Liu, Chan Wei, Qiang Ma, Weimin WangAbstractBackgroundThe present study aims to explore the possible mechanisms of Hippo-YAP1 signaling pathway in the development of severe preeclampsia (sPE).MethodsA total of 14 pregnancies complicated with severe preeclampsia as well as 14 healthy pregnancies were involved in this research from Department of Obstetrics, the First Affiliated Hospital of Xi’An Jiaotong University, from 15th March 2016 to 15th March 2018. The mRNA levels of YAP1, TAZ, MST1 and MST2 were tested via the RT-qPCR in the ...
In conclusion one-piece immediate loading implant is a reliable device for mandible rehabilitation. PMID: 31833326 [PubMed - as supplied by publisher]
Publication date: Available online 13 December 2019Source: Prostaglandins, Leukotrienes and Essential Fatty AcidsAuthor(s): Christopher E. Ramsden, Maria Makrides, Zhi-Xin Yuan, Mark S. Horowitz, Daisy Zamora, Lisa N Yelland, Karen Best, Jennifer Jensen, Ameer Y. Taha, Robert A. GibsonAbstractOxidized lipids derived from omega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids, collectively known as oxylipins, are bioactive signaling molecules that play diverse roles in human health and disease. Supplementation with n-3 docosahexaenoic acid (DHA) during pregnancy has been reported to decrease the risk of preterm birth i...