Successful Oral Desensitization with Dasatinib in Delayed Cutaneous Hypersensitivity Reactions.

Successful Oral Desensitization with Dasatinib in Delayed Cutaneous Hypersensitivity Reactions. Ann Allergy Asthma Immunol. 2019 May 17;: Authors: Karaatmaca B, Aytac S, Sahiner UM, Sekerel BE, Soyer O PMID: 31108179 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research

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The prevalence of allergic diseases such as asthma, allergic rhinitis, food allergy and atopic dermatitis has increased dramatically in recent decades. Conventional therapies for allergy can induce undesirable effects and hence patients tend to seek for natural compounds as alternative medicine. Considering the fact above, there is an urgency to discover potential medicinal plants as future candidates in the development of novel anti-allergic therapeutic agents. Lamiaceae family, the mint family, is a diverse plant family which encompasses more than 7000 species and with a cosmopolitan distribution. A number of species fro...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
AbstractPurpose of ReviewEosinophils are short-lived granulocytes that contain a variety of proteins and lipids traditionally associated with host defense against parasites. The primary goal of this review is to examine more recent evidence that challenged this rather outdated role of eosinophils in the context of pulmonary infections with helminths, viruses, and bacteria.Recent FindingsWhile eosinophil mechanisms that counter parasites, viruses, and bacteria are similar, the kinetics and impact may differ by pathogen type. Major antiparasitic responses include direct killing and immunoregulation, as well as some mechanism...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
In conclusion, young adults with history of allergies were more likely to enter exposed jobs, suggesting no avoidance of potentially hazardous exposures. Improved counselling against high risk jobs may be needed for young adults with these conditions.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Communication Source Type: research
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
BOSTON (CBS) — It’s that time of year: kids are heading off to camp and the American Academy of Pediatrics is updating its recommendations on how to keep kids safe during the summer. First, all campers should have a pre-camp check-up with their pediatrician to address any health issues and update immunizations, whether it’s a day camp or an overnight camp. The AAP also suggested parents communicate directly with camp administrators to discuss any special health concerns, like food safety if a child has food allergies, or how daily medications will be stored and administered for kids who have underlying he...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Seen On WBZ-TV Syndicated Local American Academy Of Pediatrics Dr. Mallika Marshall Summer Camp Source Type: news
ConclusionAllergic eczema/asthma in early life, being born during the autumn/winter, having multiple allergic symptoms and two allergic parents were all strong predictors for having allergic diseases at 5 and 10 years of age. However, the allergic march seems to be independent of heredity, as IgE ‐mediated allergies follow the same trajectories in children with and without allergic heredity.
Source: Immunity, Inflammation and Disease - Category: Allergy & Immunology Authors: Tags: ORIGINAL RESEARCH Source Type: research
ConclusionsTen ‐year prospective outcomes of ESS for CRS demonstrate that the initial clinically significant improvements in QOL seen 6 months postoperatively are durable over the long term. Over 75% of patients reported clinically significant long‐term QOL and HUV improvement. HUV returned to normal. Revision surgery rate was 17% and worse postoperative endoscopy scores within 18 months of initial ESS were associated with higher likelihood of revision surgery. Most patients would pursue ESS again and recommend the procedure to other patients considering this treatment option.
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Pediatric Allergy, Immunology, and Pulmonology,Volume 32, Issue 2, Page 56-62, June 2019.
Source: Pediatric, Allergy, Immunology, and Pulmonology - Category: Respiratory Medicine Authors: Source Type: research
Pediatric Allergy, Immunology, and Pulmonology,Volume 32, Issue 2, Page 63-69, June 2019.
Source: Pediatric, Allergy, Immunology, and Pulmonology - Category: Respiratory Medicine Authors: Source Type: research
AbstractPurpose of ReviewCharcot-Leyden crystals (CLCs), slender bipyramidal hexagonal crystals, were first described by Jean-Martin Charcot in 1853, predating Paul Ehrlich ’s “discovery” of eosinophils by 26 years. To date, CLCs are known as a classical hallmark of eosinophilic inflammation. CLC protein expresses palmitate cleaving lysophospholipase activity and is a member of the family of S-type lectins, galectin-10. We summarize current knowledge regarding t he pathological observations of CLCs and their mechanism of generation focusing on eosinophil cell death.Recent FindingsThe presence of CLCs...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
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