Cannabis users in their 30s 'have lungs of 80-year-olds'
Smokers of the drug in their 30s have lungs so badly damaged they are put on long-term oxygen therapy while one patient in Bangor, north Wales, is awaiting a lung transplant, a study found.
Conclusions ECMO as BTT has led to encouraging perioperative outcomes and early survival. Careful patient selection and early use of ECMO seems to allow for preservation of vitality while these critically ill candidates await donor organs, which may improve outcomes.
Conclusions Preoperative functional independence and maintenance of employment are associated with superior long-term outcomes in lung recipients. The results highlight potential benefits of pretransplant functional rehabilitation for patients on the waiting list for lungs.
Invasive aspergillosis (IA) is a frequent complication in lung transplant recipients (LTRs). Clinical risk factors for IA have not been fully characterized, especially in the era of extensive antifungal prophylaxis.
We examined safety and long-term outcomes of intravenous treprostinil administered via the implantable LENUS Pro ® pump in patients with severe pulmonary hypertension (PH).
The Fried frailty phenotype is associated with morbidity and mortality in lung transplant (LTx) candidates, but its clinical application and association with post-transplant outcomes are not well defined. We aimed to assess two alternate frailty indices in LTx candidates and evaluate associations of frailty with early post-transplant outcomes and one-year mortality.
Interstitial lung diseases (ILDs) are a heterogeneous entity of diffuse parenchymal lung diseases characterised by damage of the parenchyma as a result of varying patterns of inflammation and fibrosis . Idiopathic pulmonary fibrosis (IPF) is a specific subgroup of ILDs and has a devastating prognosis  with a median survival time of 2–3 years [2–4]. Pirfenidone (Esbriet) and nintedanib (Ofev) were approved for IPF treatment, showing a stabilisation of the disease [5, 6], and are the treatments recommended by international guidelines . Nintedanib was shown to increase the risk of bleeding events in ...
Clinical Transplantation, EarlyView.