Cannabis users in their 30s 'have lungs of 80-year-olds'

Smokers of the drug in their 30s have lungs so badly damaged they are put on long-term oxygen therapy while one patient in Bangor, north Wales, is awaiting a lung transplant, a study found.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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ConclusionsOlder age, lower FEV1 % of predicted, and lower MEP were independently linked to unfavorable outcomes. FACED and BSI were not accurate in predicting mortality in our cohort.
Source: Lung - Category: Respiratory Medicine Source Type: research
Publication date: Available online 14 November 2018Source: The Annals of Thoracic SurgeryAuthor(s): Joshua Hsu, Aravind Krishnan, Cheng T. Lin, Pali D. Shah, Stephen R. Broderick, Robert S.D. Higgins, Christian A. Merlo, Errol L. BushAbstractBackgroundSarcopenia, a known component of frailty, defined by diminished cross-sectional area of the psoas muscles, is associated with poor outcomes after a range of surgical procedures. However, little is known of the relationship between sarcopenia of the psoas muscles (SPM) and long-term mortality, decline in pulmonary function, and graft failure after lung transplantation.MethodsW...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsOur results suggest that even though donor and recipient age may be important in lung transplantation, the interplay between donor and recipient age alone is not an independent determinant of survival. Careful selection of lungs from donors over 60 years old should be exercised, taking into consideration the totality of donor demographics and risk factors rather than dismissing lungs based on advanced age alone
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsMucormycosis involved mainly the sinu ‐orbital site and affected children>10  years. Despite aggressive treatment with high‐dose L‐AmB and timely surgical debridement, the mortality rate remains still high.
Source: Mycoses - Category: Research Authors: Tags: ORIGINAL ARTICLE Source Type: research
Collaboration Combines CollPlant’s Proprietary rhCollagen-based BioInk Technology and United Therapeutics’ Regenerative Medicine and Organ Manufacturing Capabilities NESS ZIONA, Israel, November 12, 2018 -- (Healthcare Sales &Marketing Network) -- Col... Devices, Regenerative Medicine, Licensing CollPlant, United Therapeutics, Lung Biotechnology PBC, 3D bioprinting
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
ConclusionPatients who are at risk for SCA are patients who have had a cardiac arrest due to ventricular fibrillation (VF) or sustained ventricular tachycardia (SVT), those with familial or inherited condition with sudden cardiac arrest risk, myocardial infarction with an ejection fraction (EF) of less than or equal to 35%, dilated cardiomyopathy (including NICM), with an EF of less than or equal to 35%, ICD explanations, and other conditions with high risk of ventricular tachycardia (VT) or VF are candidates for the WCD.The sample of data was from 186 patients. However, more patients were likely candidates but may not hav...
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
ConclusionA diagnosis of LC following LTx remains rare. LC in the explanted lung seems to have no impact on survival for early ‐stage disease. LC in the transplanted or native remaining lung after LTx has poor prognosis.This article is protected by copyright. All rights reserved.
Source: Clinical Transplantation - Category: Transplant Surgery Authors: Tags: Original Article Source Type: research
ConclusionPirfenidone and nintedanib do not modulate expression of senescence markers, levels of p ‐SMAD3 or the amount of fibrosis in IPF lungs. Treated patients have less histopathological evidence of acute lung injury at the time of lung transplantation.
Source: Histopathology - Category: Pathology Authors: Tags: Original Article Source Type: research
This study aimed to evaluate preoperative nutritional assessment as a predictor of LTX outcomes.
Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Original article Source Type: research
CONCLUSION:  In a post-LTx setting, LUS represents a clinical novelty as a feasible diagnostic and monitoring tool to identify pathological pulmonary complications in the early post-operative phase. PMID: 30414162 [PubMed - as supplied by publisher]
Source: Ultraschall in der Medizin - Category: Radiology Authors: Tags: Ultraschall Med Source Type: research
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